Saccharopolyspora spinosa is an important producer of antibiotic spinosad with clarified biosynthesis pathway but its complex regulation networks associated with primary metabolism and secondary metabolites production almost have never been concerned or
Circulated iron was combined with transferrin in the form of Fe3+, and then it entered into cells by TFR1. Iron in Fe3+ form was deoxidized to iron in Fe2+ by iron oxide reductase STEAP3. Ultimately, Fe2+ was released into a labile iron pool in the cytoplasm from the endosome ...
Overall cervical HPV-DNA detection in pregnant women recruited in the HPV screening survey was 6.5% (54/828). Sexual behavior-related variables, previous histories of genital warts or sexually transmitted infections, and presence of cytological abnormalities were statistically significantly and positively ...
(Figure1). The results showed that Xcaw12879 is closely related to XccA306. Interestingly, these two citrus canker pathogens form a clade withX. citripv. mangiferaeindicae LMG 941 andX. axonopodispv. punicae LMG 859, which cause bacterial black spot in mango and bacterial leaf blight in...
However, when these cells were co-treated with iron-chelating agents, the accumulation of ROS and cell death were inhibited. Thus, a new, nonapoptotic, iron-dependent form of cell death was inferred and given the name ferroptosis. The primary instigator of ferroptosis is the iron-dependent ...
Jian Yun Qing Hua Decoction (JYQHD), a traditional Chinese medicine decoction, which has been applied in the treatment of gastric cancer (GC). We attempt to confirm the anti-gastric cancer effect of JYQHD and explore the mechanism of JYQHD. Acute toxicit
IL1B is a member of the IL1 cytokine family, which is produced by activated macrophages as a pre-protein, and is hydrolyzed by cystathionine aspartase 1 into its active form. This cytokine is an important mediator of the inflammatory response and is involved in a variety of cellular activitie...
During male meiosis, the Y chromosome can form perfect pairing with the X chromosome. However, it is unclear whether mammalian Female germline stem cells (FGSCs) without a Y chromosome can transdifferentiate into functional haploid spermatid-like cells (
4) and ononin (33), in Astragali Radix, could be hydrolyzed to form calycosin (34) and formononetin (35), respectively, during decocting. The hydrolysis efficiency was strongly affected by pH, temperature, and the amount of herbs [19]. Two compounds of TCM, Sanhuang Xiexin Tang (SXT...
The human gastrointestinal tract harbors complex and diverse microbes that act as a key factor in maintaining the homeostasis of the intestinal microenvironment [1]. It is estimated that approximately 1013–1014 bacterial cells from more than 1000 different species are present in gut, which form a ...