The development of the cortex is a delicate balance between proliferation, differentiation, and migration of neural progenitors (NPs). Throughout developmental process, various cellular mechanisms ensure that NPs differentiate into the correct cell subtypes, migrate to their correct regions, and form the...
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S4l). Furthermore, WNV infection of WT and Cxcr6 −/− mice did not reveal significant differences in survival, weight loss, acute levels, or clearance of viral loads in the CNS (Additional file 1: Fig. S4a, b, c, d). These data suggest that CXCR6 is not required for the ...
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While BMP signaling plays a central role in instructing pluripotent cells to form epidermis, it is the other branch of the TGF-beta that directs mesendodermal fates. Members of the Activin/ Nodal/Vg1/GDF1/TGF-beta subfamily act via pSmad2/3 to activate mesodermal and endodermal target ge...
(Additional file14: Table S9). This finding is of great interest since it has been demonstrated that two-components systems and sRNAs are interconnected in order to form networks that integrate and transduce information from the environment into fine-tuned changes of gene expression[34,35]. ...
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