There was no change in the choice of and prioritization of outcome measures in the course of the trial. From the time the subject signs the informed consent form, all adverse events (AEs) that occurred were captured on case report forms and included in the summaries. AE evaluation comprised ...
When aggregating cytokine profiles across all three time points the subset of IL-13, 10 and 23 measured at rest were again retained and additional context was recruited in the form IFN-γ at peak effort and IL-15 post-exercise. Used together, these cytokines measured across all three phases ...
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The grapevine (Vitis vinifera) is an economically important crop of global significance, cultivated across the world to produce grape-based commodities such as wine, raisins, and grape juice. Historically, its productivity has been endangered by its high susceptibility to biotic and abiotic stresses, ...
vinifera. In contrast, APRT3y is specifically activated in males, suggesting that this allele form may trigger a decrease in cytokinin concentration in the carpel and cause its abortion (Figs. 4c, d and 5). Downregulation of VviPLATZy, APRT3y, and perhaps VviFSEX may be sufficient to ...
The results obtained from the identity-by-state (IBS) analysis showed the genetic relationships among the different chicken breeds. As shown in Fig.4, among all the Guizhou indigenous chicken breeds, close genetic relationship was only found in partial individuals of XY, PD and CSWG populations ...
recruiting ASP1, a transcriptional co-repressor. Moreover, WG1 is ubiquitinated by E3 ubiquitin ligase GW2 and is subsequently degraded. Genetic analysis demonstrated that the three proteins form a GW2-WG1-OsbZIP47 molecular regulatory module to coordinate grain size and weight (Hao et al.2021...
Notably, circulating levels of FFAs, including palmitate, are greatly elevated in T2D, and can drive EC dysfunction [15, 19]. Recently, lipid droplets were shown to dynamically form and disassemble in ECs following exposure to FFAs [40]. We transfected HUVEC with control or miR-30e mimic and...
Deletions of this type can often be attributed to genomic instability; typically this instability is associated with the formation of alternative, non-B DNA secondary structures [28]. As a general rule, DNA sequences that form such secondary structures are repetitive [28]; yet, analysis of the...
[16]. For instance, in butterflies, the visual organs of the larval stage typically consist of up to six stemmata per eye, each with a lens and seven photoreceptors that form a tiered rhabdom [17], compared to the much more complex adult compound eyes, which consist of hundreds of ...