RNA profiling technologies at single-cell resolutions, including single-cell and single-nuclei RNA sequencing (scRNA-seq and snRNA-seq, scnRNA-seq for short), can help characterize the composition of tissues and reveal cells that influence key functions
Guardians of the Galaxy Vol. 2 (2017) cast and crew credits, including actors, actresses, directors, writers and more.
When aggregating cytokine profiles across all three time points the subset of IL-13, 10 and 23 measured at rest were again retained and additional context was recruited in the form IFN-γ at peak effort and IL-15 post-exercise. Used together, these cytokines measured across all three phases ...
1). In their simplest form, deletions and inversions were found to be the most common SV types, while consistent with other PCa studies, we observed a low frequency of insertion events (Additional file 1: Fig. S2). Only 15 tumours (8.3%) presented with at least one insertion, which may...
For instance, there is a long-standing history of terrier and mastiff-type breeds being crossed in the mid-1800s to form multiple bull terrier- and terrier-like breeds such as the Staffordshire Bull Terrier and the Boston Terrier (see the Bull Terrier subclade). There is also excessive ...
Tertiary lymphoid structures (TLSs) are organized aggregates of immune cells that form postnatally in nonlymphoid tissues [16, 17]. The presence of B cells within TLSs has been observed in various cancers [13, 18, 19]. Analysis of single-cell transcriptome data from NSCLC patients revealed ...
A future route along this line would be to choose the appropriate form of parallel execution of transactions, e.g. inter-transaction parallel execution for uncontended workloads or where contention is “beneficial” (i.e. due to resource sharing), intra-transaction parallel execution for contending...
CRC development may take decades to transform into the final form of cancer. Many factors could modify the pace of this process, including diet, alcohol, and tobacco consumption, as well as contaminants present in water and food [5, 6]. Recently, the gut microbiota (GM) has also been ...
Microbiome alterations have been associated with depression, and fecal transfer of depressed patients’ microbiomes is sufficient to enhance despair behaviors in rodents. Yet little is known about the potential mechanisms, whereby microbes modulate depre
As an alternative solution, we developed the approach of harvesting full-thickness skin tissue in the form of “micro skin tissue columns” (MSTCs). Even when large numbers (hundreds–thousands) of MSTCs are harvested, the small size (< 1 mm diameter) of each MSTC enables the donor site...