Intestinal lymphangiectasia (IL) is a rare protein-losing enteropathy caused by disorders of the intestinal lymphatics. There are only a few case reports and case series concerning the VCE (video capsule endosc
secretion of type 1 interferon (IFN) and other pro-inflammatory cytokines. This can paradoxically have a detrimental or beneficial effect on the vaccine’s efficacy. On one hand, by inducing APC activation and maturation, it enhances antigen processing and presentation and boosts the resulting immune...
Schematic diagram of IVT mRNA in cancer vaccine. (A) Conventional mRNA. (B) Self-amplifying mRNA includes four genes encoding four non-structural proteins (nsP1–4) required for the formation of a functional replicase. Subsequently, the replicase uses the mRNA as a template to self-amplify. T...
Trained data collectors use a standardised form for digital entry that contains parameters relating to demographic, anthropometric and admission data, treatments, and outcomes. The Clinical Information Network (CIN) is a research partnership between the KEMRI-Wellcome Trust Research Programme, the Kenyan ...
At least as much as the energy we used on earth is lost in the form of waste heat1. Thermoelectric (TE) power generators that enable the direct conversion from heat to electricity have been studied for a long time, much twethiavherilertirmyee,raaStlnh,lyadσ-n,daκtrbhitsvoeote(clnu...
In the C4 pathway that exists in: humans, animals, fungi, and α-proteobacteria, ALA synthase (ALAS) catalyzes the condensation of glycine (Gly) and succinyl-CoA (Suc-CoA) to form ALA. In the C5 pathway found in archaea, plants, and many bacteria, ALA is synthesized from l-glutamate (...
(d) Level of the phosphorylated form of eIF2 (p-eIF2) relative to the total levels of eIF2. In order to compare different experiments, the relative p-eIF2/eIF2 ratio was normalized using the average of each donor at the start of the culture (day 0). Conditions labeled as 0 µ...
There has been a significant surge in the global prevalence of diabetes mellitus (DM), which increases the susceptibility of individuals to ovarian cancer (OC). However, the relationship between DM and OC remains largely unexplored. The objective of this
Gap junction protein alpha 3, encoded by Gja3, is specifically expressed in the plasma membrane of lens fiber cells to form gap junctions [40]. Gap junctions directly connect the cytoplasm of adjacent cells, and allow various molecules and ions to pass freely between cells, functioning for the...
coronary syndrome [84,85]. Common markers of endothelial activation include ICAM-1 (Intercellular Adhesion Molecule 1), VCAM-1 (Vascular Cell Adhesion Molecule 1) and E-selectin [65]. The solubilized form of these proteins, found within serum, is often used as a measure of endothelial damage...