Cited in 14 publications. TDP-43 (full length) antibody for WB, IHC, IF/ICC, IP, ELISA and reacts with human, mouse, rat.
Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid propertiesMotor neuron diseaseTDP-43 fibrilsTDP-43 filamentsprotein misfoldingprotein aggregationAccumulation of ubiquitin-positive, tau- and 伪-synuclein-negative intracellular inclusions of TDP-43 in the central ...
These structures typically form in response to pathogens, tissue damage, and necrosis, but this defense response can also be triggered by different genetic perturbations [46, 48,49,50]. Irrespective of the trigger, melanotic masses often form in the larval hemolymph and can be readily observed ...
Transactive response DNA-binding protein 43 kDa (TDP-43) has been identified as the major component of ubiquitinated inclusions found in patients with sporadic amyotrophic lateral sclerosis (ALS). Increasing evidence suggests prion-like transmi
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The ECX350F is an OLED Microdisplay designed for use in augmented reality (AR) glasses, an application which demands a thin, lightweight form factor without compromising visibility. Adopting a novel OLED structure and microlenses, the microdisplay enhances pixel light emission despite its diminutive...
Amyloid-β (Aβ) associates with extracellular vesicles termed exosomes. It is not clear whether and how exosomes modulate Aβ neurotoxicity in Alzheimer’s disease (AD). We show here that brain tissue and serum from the transgenic mouse model of familia