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We also found that the tendency to form two clustered phenotypes largely remains regardless of stress types (Additional file 1: Fig. S4). These results indicate that domesticated (and unassigned) yeast strains exhibit a clear fitness trade-off against various general environmental conditions, while ...
It will be better if you generate an SRS (software requirements specification). It is a document that has details like: Product features The development process roadmap Team members and their roles And more! This document will help you estimate the custom web application development cost better...
Within evidence-based practice (EBP), systematic reviews (SR) are considered the highest level of evidence in that they summarize the best available research and describe the progress in a determined field. Due its methodology, SR require significant time and resources to be performed; they also ...
Although the intact form of CD6 is the most abundant in T cells, an isoform lacking d3 (CD6∆d3) is transiently expressed on activated T cells. Still, the precise character of the signaling transduced by CD6, whether costimulatory or inhibitory, and the influence of its ectodomain on ...
C Formulation of interaction specialization of host in host-virus network, which is calculated by Shannon index d (see details in the ‘Methods’ section) Full size image We further expect that GrSRs could be influenced by the host growth environment and genetic traits [4, 23, 24]. For ...
Although a substantial increase in the survival of patients with other cancers has been observed in recent decades, pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest diseases. No effective screening approach exists. Differential exosom
While finding the reads that map over multiple genes, indicating potential gene fusions, is straightforward, the challenging part of gene fusion discovery is to identify such reads supporting true fusions, which form a minority of the multi-gene reads. For example, in our experiments on PacBio ...
of single-cell RNA sequencing (scRNA-seq) technology has revolutionized biomedical research by enabling detailed examination of cellular and molecular diversity. Nevertheless, investigating mechanisms at the single-cell level in highly mineralized skeletal tissue poses technical challenges. In this ...
The analysis of printed or digitized chemical structures is an important task in education, research and development of chemical products. Molecular structures contained in conventional scientific publications, documents and textbooks usually come in the form of images and annotated text. Structural formulas...