Based on synteny analysis, both the location and orientation of LAT and its adjacent genes, including SH2B1, ATXN2L, SPNS1, NFATC2IP, and SGF29, were evolutionarily conserved among the teleost species (Figure 1A). In addition to LAT, other components that form the signalosome in mammals, ...
Drug induced bile duct injury is a frequently observed clinical problem leading to a wide range of pathological features. During the past decades, several agents have been identified with various postulated mechanisms of bile duct damage, however, mostly
Multiple excipients such as compritol ATO 888, vitamin E TGPS and transcutol P were used to form a solid lipid core in which UroA or UAS03 could be encapsulated (Fig. 1A). The surfaces of the particles were coated with GKG polymer. GKG provides stability to the particles and renders a ...
a severe, devastating bacterial pneumonia in a 39-year-old European polymorbid woman with a rare form of diabetes mellitus, which had been poorly compensated for a long time with limited compliance, in the context of a combined immunodeficiency that strongly influenced the course of the disease....
Shoot growth-form (SGF) This trait describes the canopy structure of shoots (Kleyer1995). Shoot growth-forms can be (1) submerged, attached to the substrate; (2) free-floating plants; (3) floating leaves, attached to the substrate; (4) emergent, attached to the substrate (amphibious); ...
Simulated Gastric Fluids/Simulated Intestinal Fluids (SGF/SIF) Resistance The experimental procedure for this assay is based on the methodology described by Tan et al. [34, 46] and aims to evaluate the survival of isolated microbes in the human GIT environment by subjecting them to SGF and SIF...
(B) In vitro release kinetics of curcumin from low molecular weight (LMW)-HA and HMW-HA NPs under simulated gastrointestinal conditions (SGF, simulated gastric fluid; SIF, simulated intestinal fluid; SCF, simulated colonic fluid). (C) Particle size of HMW-HA NPs when being exposed to SGF ...
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In microencapsulation technology, polymers are mainly used to encapsulate functional, active substances and form a dense physical barrier around the core material to reduce the reaction of the core material with the external environment. Microencapsulation of active substances can improve their physical ...
Various isomers of α, β, and γ chains combine to produce different isotypes of heterotrimeric laminin [6]. Laminin C (LAMC) is the main form of laminin. Three genes have been identified, namely LAMC1 (formerly known as LAMB2), LAMC2 (also known as LAMB2T and LAMNB2), and LAMC3....