An SNP-based tree showed the ISS isolates form a separate clade even from the closest Earth strain, indicating isolates from other sources (e.g. leaves, human urine, seawater) did not cluster with ISS strains in our SNP-based analysis (Supplementary Fig. 1). These results reveal that E. ...
Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12. J Clin Oncol. 2019 Dec 1;37(34):3212–3222. https://doi.org/10.1200/JCO.19.00308. Epub 2019 May 31. PMID: 31150315. ...
Probiotic extracellular vesicles (pEVs) are biologically active nanoparticle structures that can regulate the intestinal tract through direct or indirect mechanisms. They enhance the intestinal barrier function in livestock and poultry and help alleviate
Oral infection with cysts is the main transmission route of Toxoplasma gondii (T. gondii), which leads to lethal intestinal inflammation. It has been widely recognized that T. gondii infection alters the composition and metabolism of the gut microbiota,
strains, all the detected glycolytic genes were found to be dispersed in their genomes. This suggests that the expression of these genes is probably executed and regulated independently. The EMP pathway consists mainly in glucose catabolism and production of energy in the form of two adenosine 5'...
Artemisinic acid and dihydroartemisinic aldehyde form arteannuin B and artemisinin, respectively, in a non-enzymatic reaction in Glandular-secreting trichomes [11,12,13]. ADS is the first step gene in the synthesis pathway of artemisinin, and is a significant component in the artemisinin ...
Taxol serves as an efficient natural anticancer agent with extensive applications in the treatment of diverse malignancies. Although advances in synthetic biology have enabled the de novo synthesis of taxol precursors in various microbial chassis, the to
citing a perceived lack of personal benefit. From those who agreed to participate and met the inclusion and exclusion criteria (n = 373), 116 signed the electronic informed consent form and completed the full set of questionnaires. Two patients, not meeting the Long COVID criteria based on...
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in 1959 [1], as a focal area of myelinolysis in the pons, differing in its distribution and clinical presentation from any other previously recognized form of demyelination. Initially reported as a disease related to alcohol abuse and malnutrition, it was later identified by Kleinschmidt-DeMasters...