Normalisation of all data was performed independently using the robust multi-array average (RMA) expression measure[51]. Probesets were then annotated using latest annotation available in Bioconductor (26 June 2009) and samples ordered according to cell-type grouping to ease interpretation of the ...
Raw microarray intensity values are pre-processed using the Robust Microarray Average (RMA) method [22]. Subsequent t-test or ANOVA statistical testing (this is dependent on the user-defined experimental design table) is performed. To determine a statistical significance (p-value) cut-off an equi...
However, there are those who evolve to the severe form of VL, with a high lethality rate [5]. In addition, relapse is also observed in medical practice [6, 7]. Clinical and laboratory markers such as age, bleeding, edema, jaundice, dyspnea, bacterial infection, HIV/AIDS co-infection, ...
VviERF6Lgene expression in response to rapid dehydration CS leaves. Log2(RMA-normalized signal intensity+ 1) gene expression of threeVviERF6Lsin CS leaves treated with control (solid lines and circles), or detached and allowed to rapidly dehydrate under regulated conditions (dotted lines and ...
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where G represents the functional form for a nonlinear model. As proposed by van Doorslaer et al. [32], we have restored the mechanics of the decomposition framework by replacing the βk parameters in the equation with the βmk parameters, where the βmk represent the partial effects of the...
Tetralogy of Fallot (ToF) is the main form of cyanotic CHDs (estimated incidence 5 per 10,000 live births), characterized by a conal septum malalignment which leads to aorta rightward deviation. This defect results in a large ventricular septal malformation and stenosis of the pulmonary valve ...
report large and reproducible base-specific read biases associated with random hexamer priming in illumina's standard library preparation protocol. the bias takes the form of patterns in the nucleotide frequencies of the first dozen or so bases of a read. they provide a re-weighting scheme, where...
This work presents an independent confirma- tion of the analytic theory of singularity formation described in [16]. 2. Lump solutions Upon performing the change of variables t →3 √ 3t, x →− √ 3x, y → √ 3y, the governing equation (5) becomes, u t = u xxx +u xyy + u...
Most bacteria exist in the form of a biofilm, which often contains diverse species that interact with each other and their environment. Biofilms are specifically microbial aggregates that rely on a solid surface and extracellular products, such as extracellular polymeric substances (EPSs).Citation5 Ba...