CMs are vulnerable to damage from hypoxia or oxidative injury, as in the case of postoperative reoxygenation [3]. Damaged CMs are then removed and replaced by fibroblasts during the natural healing process of the heart. Unfortunately, fibroblasts eventually form a non-functional fibrotic scar that ...
After ingestion of cysts, the parasite may undergo excystation in the gastrointestinal tract and may develop into a vacuolar form that divides by binary fission. The following stage could be either the amoeboid form or the granular form. Then, encystation may occur during passage along the ...
All blood samples were drawn from a single finger prick to collect a total of ≤ 30 μl of blood. Participants who tested positive based on RDT results were offered free treatment according to the National Malaria Treatment Guidelines, and the first dose was given via directly observed ...
The importance of this disease-overlap will depend upon the epidemiology of pathogens in each particular setting, but also on the severity of the presentation and the age of the patient. One consequence of falling malaria transmission rates [18,19] is that presumptive treatment is not as safe a...
Falls in older adults are a critical public health problem. As a means to assess fall risks, free-living digital biomarkers (FLDBs), including spatiotemporal gait measures, drawn from wearable inertial measurement unit (IMU) data have been investigated t
In Cambodia, ACD and PCD rely on immunochromatography-based rapid diagnostic tests (RDT) whose detection threshold has been documented at about 100 parasites/µL [11], making this method not sufficiently sensitive to detect most asymptomatic infections [5] with an elevated rates of false ...
Almost all people in developed countries are exposed to metal nanoparticles (MeNPs) that are used in a large number of applications including medical (for diagnostic and therapeutic purposes). Once inside the body, absorbed by inhalation, contact, ingest
Ectopic pregnancy (EP) is a form of abnormal pregnancy in which the fertilised ovum implants outside the intrauterine cavity, with the ampullary region of the Fallopian tube being the most common site of implantation (Figure1) [1]. EP represents 1-2% of all pregnancies and haemorrhage from an...
Drug resistance represents a major obstacle in cancer management, and the mechanisms underlying stress adaptation of cancer cells in response to therapy-induced hostile environment are largely unknown. As the central organelle for cellular energy supply,
The cells in the spheres also retain the ability to differentiate in vitro to form cells representative of the three germline layers after five passages. Conclusions These data suggest that USSC growth mediumACF maintains USSCs in an undifferentiated state and supports growth in suspension. This is...