The partially glycosylated precursor form of LDLR is synthesized in the ER. This immature protein transits from the ER to the Golgi complex, where it gets fully glycosylated to the mature protein and gets translocated to the plasma membrane to perform its functions as the receptor of LDL. To ...
RCMP Sgt. Kim Chamberland also said the police force continues to investigate violations of the Security of Information Act associated with media reports. “This investigation is not focused on any one security agency. As the RCMP investigation is ongoing, there will be no further com...
While staying at Ver-El RV park in Concord, NC we were parked across the street fromCharlotte Motor Speedway, we noticed a lot of classic cars heading into the parking lot. Twice a year the racetrack hosts theCharlotte AutoFair, where owners can put their cars up for sale or trade. Ther...
In Canada, as many as 44% of women and 36% of men experience some form of IPV within their lifetimes [1]. IPV carries substantial short- and long-term negative impacts for those who experience it, as well as their families and their communities more broadly [2,3,4]. Moreover, IPV ...
Examples of B.C. local articles include "RCMP target fentanyl shipments from China" [61] and “China refutes claims it's a major source of fentanyl” [67], which encourage more public awareness of the “contaminated opioids which has led to surges in fatal overdoses in B.C”. Ontario ...
The latter impairment is the most serious form of DNA damage [135]. A disfigured genome is the stimulus that initiates DNA damage response (DDR) processes [136,137]. These consist of a series of complex events that heal the DNA lesions. When the damage is highly deleterious, however, it ...