well as maintaining the information of the structured illumination, it is implemented in a supervised manner and necessitates noise-free ground-truth data. Second, if these algorithms are employed in the post-reconstruction procedure (Supplementary Fig.1b), taking N2V [39] or its 3D-form derivat...
Piff is a Python software package for modeling the point-spread function (PSF) across multiple detectors in the full field of view (FOV). Features: (Some are aspirational. We're still working on the code!) Has multiple basis sets for the underlying PSF model, including pixel-based, shapelet...
url_templateA string with placeholder{sdk_key}can be provided so that this template along with the provided sdk key is used to form the target URL. You may also provide your own logger, error_handler, or notification_center. AuthDatafilePollingConfigManager ...
Oomycetes are a large group of economically and ecologically important species. Its most notorious member is Phytophthora infestans, the cause of the devastating potato late blight disease. The life cycle of P. infestans involves hyphae which differentia
It is known that calcitriol, the active form of vitamin D, plays an important role in modulating the immune response in several inflammatory diseases. The aim of this preliminary study was to evaluate in vitro the influence of calcitriol on the immune response of human vaginal epithelial cells ...
Although the etiology of PD remains enigmatic, parkin mutations have been linked to autosomal recessive juvenile parkinsonism (AR-JP) [32, 49]. In sporadic PD, the more common form, parkin often becomes inactivated via S-nitrosylation, oxidative and dopaminergic stress, and c-Abl phosphorylation ...
form of tomography is necessary. This is more challenging than, say, the medical case, for two main reasons: (i) as feature sizes approach the radiation wavelength, e.g. X-rays, diffraction and scattering effects influence image fidelity more strongly; and (ii) the number of voxels (...
In vitro matured human pluripotent stem cell-derived cardiomyocytes form grafts with enhanced structure and function in injured hearts. Circulation. 2022;145:1412–26. CAS PubMed Google Scholar Guo Y, Pu WT. Cardiomyocyte maturation: new phase in development. Circ Res. 2020;126:1086–106. CAS...
the HIV-1 promoter is hypermethylated at two CpG islands surrounding the HIV-1 transcriptional start site. The dotted arrows indicate that DNMTs are most likely recruited to the HIV-1 promoter but this recruitment has not been demonstrated so far. In latent conditions, the active form of NF-ka...
who received osimertinib than in controls in terms of efficacy measures [87]. In other studies, ALK inhibitors improved PSF compared with chemotherapy, and alectinib and brigatinib improved PFS compared with crizotinib and ceritinib [80]. In addition, alectinib improved OS compared with chemotherapy...