olarak adlandırılan durumla savaşmaktadır. Infernal ilk nesillerde sıradan yanma vakalarıyken ilerleyen nesiller insan formunu korurken alevleri kontrol edebilmeye başlamıştır. Ayağını istediği gibi ateşleyebilen Şeytan'ın Ayak İzi lakaplı...
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There is evidence that inflammatory arthritis in the form of ankylosing spondylitis (AS), psoriatic arthritis (PsA), and rheumatoid arthritis are both positively and negatively associated with certain female-specific cancers. However, the study results are very heterogeneous. Methods Based on up to 37...
8,9,10]. Despite the significant amount of progress made with the development of AKT inhibitors, the therapeutic benefit gleaned from these drugs, mainly in the form of dual therapies, is variable. Toxicity resulting from their
The traditionally used PSA test for the screening and diagnosis of PC has various limitations, including its low specificity. These challenges have led to over diagnosis and over treatment of low-risk PC patients. Thus, new diagnostic methods that are cost-efficient and non-invasive are needed to...
Autoantibodies are a form of antibody which react with substances formed by a person’s own body (i.e., self-antigens) [96]. These self-antigens can be exclusive for a specific-cell type within one organ of the body or can be found in all cell-types, such as chromatin or centromere...
The first step is driven by membrane tension, allowing the local swellings to form on the tubular retraction fibers, and then the second step is controlled by specific proteins of the TSPAN family, which make TSPAN-based membrane domains stabilize these swellings that finally turn into migrasome...
Immune checkpoint blockade (ICB) therapy for cancer has achieved great success both in clinical results and on the market. At the same time, success drives more attention from scientists to improve it. However, only a small portion of patients are respon
1). In their simplest form, deletions and inversions were found to be the most common SV types, while consistent with other PCa studies, we observed a low frequency of insertion events (Additional file 1: Fig. S2). Only 15 tumours (8.3%) presented with at least one insertion, which may...
Psoriatic arthritis (PSA) is a chronic, immune-mediated inflammatory joint disease that is liked to mortality due to cardiovascular disease. Diagnostic markers and effective therapeutic options for PSA remain limited due to the lack of understanding of the pathogenesis. We aimed to identify potential ...