The thyrotropin-releasing hormone (TRH) stimulates not only thyrotrophs in the anterior pituitary but also the lactotrophs which produce PRL. In hypothyroidism, there is a loss of feedback inhibition on TRH production from the hypothalamus. Increased TRH levels stimulate pituitary lactotrophs ...
hormone,GHgrowth hormone,LHluteinizing hormone,M-Rmuscarinic cholinergic receptor,MSmultiple sclerosis, N1-R nicotinic cholinergic receptor type 1,NAnorepinephrine,OXToxytocin,PVNparaventricular nucleus,PRLprolactin,PNSperipheral nervous system,PSNSparasympathetic nerve system,PROX1prospero homeobox 1,SONsupraoptic...
The anti-tumor effect of drug treatment was calculated by drug-treated/control (T/C) ratio (T/C = RTVtreated / RTVcontrol × 100%). The mouse viscera were analyzed by HE staining to evaluate the safety of the inhibitor. The growth (Ki-67) and hormone (Pomc) of each tumor ...
Borghetti P, De Angelis E, Saleri R, Cavalli V, Cacchioli A, Corradi A, Mocchegiani E, Martelli P (2006) Peripheral T lymphocytes changes in neonatal piglets: relationship with growth hormone (GH), prolactin (PRL) and cortisol changes. Vet Immunol Immunopathol 110:17–25 CAS PubMed Google...
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The prevalence is estimated at 1:140,000–250,000. It is most often diagnosed in mi...
Sex differences in endogenous descending pain modulation have been observed in the form of diffuse noxious inhibitory controls (DNIC). DNIC dampens pain signaling in the dorsal horn of the spinal cord via inhibitory neurotransmitters. Research has found that DNIC is more pronounced in males compared...
RXRα has been confirmed to form heterodimers with PPARα or FXRα and bind to the core promoter of HBV, enhancing the activity of the core promoter [24, 25]. Therefore, we performed a ChIP assay to investigate the impact of ZNF148 on the binding of RXRα to the HBV ENII/Cp region...
hormone (FSH) surge [29]. Within granulosa cells, periodic fluctuations in estradiol and progesterone have been observed and are mediated via circadian regulation of aromatase [24]. TheBmal1-Clockdimer binds to the E-box sites of Cyp19a1and StAR promoter, regulating their transcription ...
Assay of the serum hormonal level and ovarian oxidative stress markers Serum levels of the estrogen (E2), follicle–stimulating hormone (FSH), Prolactin (PRL), and Luteinizing hormone (LH) were measured using sandwich ELISA kits (Cusabio, China) according to manufacture instructions and following ...
After 10–12 h of fasting, 5 ml of venous blood was drawn from the patient to investigate glucose, insulin, hormones [thyroxine (T4), thyroid stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), cortisol, 17 hydroxy progesterone (17OHP),...