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High dietary intake of vegetable products is beneficial against obesity and its related diseases such as dyslipidemia, nonalcoholic fatty liver disease, and cancer. We previously developed a diet-induced obesity model of zebrafish (DIO-zebrafish) that de
With the increasing use of nanomaterials, the need for methods and assays to examine their immunosafety is becoming urgent, in particular for nanomaterials that are deliberately administered to human subjects (as in the case of nanomedicines). To obtain reliable results, standardised in vitro immuno...
In addition, we made sure with this expression system that no exon 8-containing VEGF-A contamination is present, since yeasts do not code for any form of VEGF. Producing VEGF-A in mammalian cells has the drawback of possible formation of exons 8 and 8b heterodimers. This may be of ...
Formulations can contain one or more active substances (technical grade active ingredients = TGAI), co-formulants, safeners and synergists. For ease, only the singular form of the active substance will be used: formulations with a microorganism as active substance. ...
Second generation (2G) bioenergy from lignocellulosic feedstocks has the potential to develop as a sustainable source of renewable energy; however, significant hurdles still remain for large-scale commercialisation. Populus is considered as a promising 2
Microorganisms influence the chemical milieu of their environment, and chemical metabolites can affect ecological processes. In built environments, where people spend the majority of their time, very little is known about how surface-borne microorganisms influence the chemistry of the indoor spaces. Here...
directly influences the equilibrium of the dissociated and undissociated form of malonic acid, and hence the ability of this precursor to cross the plasma membrane. A possible solution to promote malonate uptake, is the reconstitution of a functional malate permease,e.g., Mae1 ofSchizosaccharomyces...
(Additional file7: Figure S4). Furthermore, the observed mass of the recombinant SA8 was 6 Da less than that of the reduced form of the peptide (MH+m/z = 5444.23 Da), indicating formation of three disulphide bonds. LC–MS/MS analysis of pepsin-digested SA8 revealed the disulphide-...
ISK is located in the northern Tien-Shan Mountains along the shoreline of Lake Issyk-Kul. The Issyk-Kul lake region is surrounded by two giant mountain chains including Kungey Ala-Too to the north and Terskey Ala-Too to the south, which together form a closed area. The mountain chains im...