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Across the globe, over 200 million annual malaria infections result in up to 660,000 deaths, 77% of which occur in children under the age of five years. Although prevention is important, malaria deaths are typically prevented by using antimalarial drugs
The internal heterogeneity of breast cancer, notably the tumor microenvironment (TME) consisting of malignant and non-malignant cells, has been extensively explored in recent years. The cells in this complex cellular ecosystem activate or suppress tumor
The 4K score utilizes four levels of kallikreins- fPSA, iPSA, tPSA, and human kallikrein 2 (hK2) along with the patient data, such as DRE, age, and initial biopsy outcomes in a specific algorithm, providing results in the form of percentages from 0 to 100%. This percentage forecasts the...
Yasunaga S, Grati M, Cohen-Salmon M, et al: A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness. Nat Genet. 1999, 21: 363-369. 10.1038/7693. Article CAS PubMed Google Scholar Mustapha M, Weil D, Chardenoux S, et al: An...
The aberrant expression of phosphofructokinase-platelet (PFKP) plays a crucial role in the development of various human cancers by modifying diverse biological functions. However, the precise molecular mechanisms underlying the role of PFKP in head and n
Sorafenib sensitivity has also recently been shown to be positively associated with ferroptosis activity [5,6]. Conceptually, ferroptosis is a metabolic form of cell death induced by oxidative stress [7]. Compared to normal cells, resistant tumor cells tend to have higher levels of antioxidant subs...
BPII 2.0 and Norwich's scales are more disease-specific than previously used measurements for PFI. These PROMs aimed to let surgeons more precisely evaluate the preoperative and postoperative functions of patients with patellofemoral instability. Adaptations of these PROMs to other languages and cultures...