In yeast, one class of such elements is a polyU sequence that can interact with poly(A) tails to form double-stranded (ds) RNA structure, and such structure inhibits the association of poly(A)-binding protein,
The study of the stone microbiome is of paramount importance for several reasons. It enhances our understanding of the role microorganisms play in geological processes, such as rock weathering, mineral transformation, and the earliest stages of soil formation or protosol [16,17,18]. Moreover, it...
By linking cis-regulatory sequence information with single-cell transcriptomes, pySCENIC deciphers critical TFs and their target genes, which together form a regulon. Our analysis on scRNA-seq of IDH-WT GBM identified regulons that define the GRNs of the myeloid compartment. To rank these regulon...
The spatial organization of molecules in a cell is essential for performing their functions. While protein localization [1] and disease-associated mislocalization are well appreciated [2,3], the same principles for RNA have begun to emerge. For instance, the spatial and temporal regulation of RNA...
The acid dissociation constant (also called the protonation or ionization constant) Ka is an equilibrium constant defined as the ratio of the protonated and the deprotonated form of a compound. Ka is usually represented as pKa = − log10 Ka [1]. The pKa of a chemical strongly influe...
In order to calculate the relative effect size of all recorded metadata within the RCPA and UniFrac ordinations, a stepwise redundancy analysis (RDA) was performed. The stepwise analysis was performed on the first three principal components of each ordination through the ordistep function in vegan...
Modeling the Golgi ribbon as a linear array of mini-stacks.ASchematic representation of WPB biogenesis at the Golgi. In the context of the Golgi ribbon, the size of mini-stacks (highlighted in the green box) delimits that of transiting VWF quanta (red); at the Golgi exit site, the conti...
Using the code we provide, the resulting process map displays cost statistics (mean, minimum, maximum, total) for each activity displayed in the form of a ‘decoration’ [45, 46], i.e. a label on the process map. For any given process model generated, the visual output provides the ...
(ord(message[i]),LCD_CHR) # Main program block, # Initialize display def main(): lcd_init() # Send text to I2C TWI 1602 16x2 Serial LCD Module Display while True: lcd_string("***ODROID-C2***",LCD_LINE_1) lcd_string("ODROID-magazine ",LCD_LINE_2) time.sleep(3) lcd_string(...
. To optimize the loss calculation, we calculated the partial terms in each GPU independently and exchanged the partial terms among all the GPUs in the group through NVLink. These partial terms were then combined to form the DICE loss results. This sped up the loss calculation by more than ...