In yeast, one class of such elements is a polyU sequence that can interact with poly(A) tails to form double-stranded (ds) RNA structure, and such structure inhibits the association of poly(A)-binding protein, leading to increased mRNA stability [14]. It has been also noticed that mRNA ...
The Spacecraft Assembly Facility (SAF) at the NASA’s Jet Propulsion Laboratory is the primary cleanroom facility used in the construction of some of the planetary protection (PP)-sensitive missions developed by NASA, including the Mars 2020 Perseverance
Using the code we provide, the resulting process map displays cost statistics (mean, minimum, maximum, total) for each activity displayed in the form of a ‘decoration’ [45, 46], i.e. a label on the process map. For any given process model generated, the visual output provides the ...
By linking cis-regulatory sequence information with single-cell transcriptomes, pySCENIC deciphers critical TFs and their target genes, which together form a regulon. Our analysis on scRNA-seq of IDH-WT GBM identified regulons that define the GRNs of the myeloid compartment. To rank these regulon...
The acid dissociation constant (also called the protonation or ionization constant) Ka is an equilibrium constant defined as the ratio of the protonated and the deprotonated form of a compound. Ka is usually represented as pKa = − log10 Ka [1]. The pKa of a chemical strongly influe...
brain abscess and cerebritis [3–7]. There is also the non-invasive form of listeriosis caused byL. monocytogenesin healthy people leading to outbreak, as the individuals developed febrile gastroenteritis [8,9]. It has also been reported thatL. ivanoviican cause infections mainly in ruminants,...
Network generation tools coupled with chemical reaction rules have been mainly developed for synthesis planning and more recently for metabolic engineering. Using the same core algorithm, these tools apply a set of rules to a source set of compounds, sto
To determine the connection between each patch and all other patches in a single input sequence, the MSA uses a scaled dot-product form of attention, as shown in Equation (1): Attention(Q, K, V) = So f tmax √Qkt v, dk (1) where Q means query vector, V is a value dimensional ...
As in many other ascomycetous fungi, no teleomorfic form or sexual reproduction cycle has been described forP. digitatum. We nevertheless found a conserved alpha-box mating-type protein (MAT1) locus in both strains (Additional file1: Figure S1) in an area of conserved synteny with otherPeni...
Modeling the Golgi ribbon as a linear array of mini-stacks.ASchematic representation of WPB biogenesis at the Golgi. In the context of the Golgi ribbon, the size of mini-stacks (highlighted in the green box) delimits that of transiting VWF quanta (red); at the Golgi exit site, the conti...