characterized by neuronal loss, gliosis and the abnormal deposition of α-synuclein in vulnerable areas of the nervous system. Neurodegeneration begins however several years before clinical onset of motor, cognitive or autonomic symptoms. The isolated form of REM sleep behavior disorder...
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Adjacent to the cell membrane, a specific amino acid sequence known as the neutral sphingomyelinase domain (NSD) in the juxtamembrane region (JMR) has been identified as an inducer of cell death [34,35]. It is noteworthy that NSD-mediated cell death occurs independently of the DD [36]. ...
Concept development is the most common form of theorising [Citation38]. If we manage to categorise a phenomenon on a conceptual level, then we can use it to understand similar phenomena. In this way developing concepts that are relevant and valid in various contexts, and not just in the curr...
The notes from these conversations form the data for this study. It is recognised that such data inherently contain the field workers’ interpretations of interviews and events. Thematic analysis was applied to analyze the data regarding the experiences of the participating champions [24]. The analyt...
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[156]. Its positive surface charge makes it possible to assist cell proliferation efficiently and encourages surface-induced thrombosis and blood coagulation. With the acidic groups of the cellular components of blood, free amino groups present on the chitosan membrane surface may form polyelectrolyte ...
Gene fusion refers to a sequence in which some or all of the sequences of two genes are fused through some mechanism (such as genome variation) to form a new gene [50, 51]. A fusion gene can induce the production of SEs, thereby driving the transcription of oncogenes. Benbarche et ...
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