The insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs), comprising IGF2BP1, IGF2BP2, and IGF2BP3, form a key family of RNA-binding proteins. These proteins are essential regulators of cell division and metabolic processes, primarily through their ability to stabilize and control ...
Improvements in neuroimaging technologies, and greater access to their use, have generated a plethora of data regarding male/female differences in the developing brain. Examination of these differences may shed light on the pathophysiology of the many il
Most of these properties are inherited from the 2D topography of their atomic thickness. Typical 2D materials including graphene analogs, transition metal compounds, and other layered-structure compounds have exhibited outstanding electrocatalytic activity toward OER or HER [[7], [8], [9]]. The ...
a rapid, high-throughput, one-step approach known as overlap extension rolling circle amplification (OERCA). This method utilized circular ssDNA as a template to generate a multitude of linear ssDNA fragments of varying lengths, which were subsequently used as templates for polymerase chain ...
We also measured the cleavage of capspase-3 by Western blotting. We found that the cleavage (~17 kDa fragment, active form) of caspase-3 (35 kDa) was decreased in the neurons with overex- pression of hTau (Fig. 3a,b), which coincidentally agree with our previous findings21,22...
Alginate dialdehyde was used to crosslink gelatin in the presence of borax to form hydrogels and applied to rats with excision wounds14. Re-epithelialization, however, was only significantly different from the no-treatment control at the earlier, but not later time points. On the other hand, ...
The educational material will be in the form of laminated worksheets. The educational material illustrates a simple explanation of the neurophysiology behind pain and suggestions of ways to manage pain in everyday life. The outlined intervention in GAPE The outlined intervention will start just before...
Cepok S, Jacobsen M, Schock S, Omer B, Jaekel S, Boddeker I, Oertel WH, Sommer N, Hemmer B: Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis. Brain. 2001, 124: 2169-2176. 10.1093/brain/124.11.2169. Article PubMed Google Scholar Nagarajan...
NMR structures published of the human prion protein exhibit a number of hydrophobic cavities in the well-folded core (amino acids 125 to 231) but the full length prion protein may also transiently form new cavities when the presumably disordered N-terminus gets in contact with the compactly ...
form a dynamic transcriptional activation complex (MBW complex) that regulates the transcription of genes involved in anthocyanin and PA biosynthesis [55]. R2R3-type MYB TFs such as AtMYB12 fromA. thalianaact independently of a bHLH cofactor and control the expression of genes encoding enzymes ...