First, the PKM2 protein in cancer tissues switches to a low-activity dimer form. Because dimeric PKM2 has low catalytic activity, it increases the formation of glycolytic intermediates by activating other PPP enzymes and glycerol synthesis, as well as creating NADPH. This inhibits the creation of ...
number of remaining cycle slip candidate pairs (NRCP) can be exactly calculated based on the magnitude of SIPE, TECR threshold, and the data sampling interval. After applying validation rules, the correct cycle slip pairs can be identified using a modified low-order polynomial fitting method. Thi...
Angiogenesis refers to the process of budding from the existing vascular system to form new blood vessels [13]. Previous studies have shown that the targeted deletion of FLI-1 in mice leads to foetal mortality, possibly due to abnormal bleeding caused by vascular integrity defects during vascular ...