In summary, we showed that FOXJ1-Cre;CEP164fl/fl mice presenting with the communicating form of hydrocephalus still demonstrated sustained glymphatic transport and AQP4 water channel expression along the microvasculature was normal when assessed in the ventral hippocampus. We also found that in p73−...
One of the essential components of the brain, the white matter (WM), represents areas primarily composed of myelinated axonal fibers [4]. These fibers form the communication pathways between different regions of grey matter (GM) [2, 4, 5]. Traditionally, WM has been associated with the tra...
It was then mixed with lipofectamine at a 1:1 ratio to form siRNA-lipid complex. All siRNA loadings were carried out immediately prior to cell exposure under sterile conditions. Size and zeta-potential characterisation of pSiNPs To reveal the size distribution and zeta-potential of pSiNPs, the...
Histological examination of animal tissues Animals were sacrificed and their organs were isolated and fixed in 10% Neutral Buffered Formalin (NBF). We observed discoloration in the liver (Fig. 8a) and kidney (Fig. 8b) of β-Clu-injected animals indicative of fatty changes. Histological examination...
Ovaries were fixed in neutral buffer formalin (NBF) or Bouin’s fluid, and were subsequently preserved in 70% alcohol. At least three ovaries from each group have been cut in serial sections to a thickness of 7 μm using a Reichert-Jung microtome. Hematoxylin and eosin (H&E) staining was...
Aquaculture, traditionally a form of biotechnology, has evolved to integrate innovative biotechnological applications, such as advanced feed formulations, aimed at improving the growth performance and health of farmed fish species. In the present study, the effects of feeding rainbow trout with novel fee...
(extracellular-signal-regulated kinases) and the expression of cell cycle regulators, such as p21 and p27, in HNSCC cells [132,134]. Additionally, atorvastatin treatment in vitro significantly decreases the active form of RhoC in HNSCC cells. Importantly, atorvastatin also mediates a significant ...
At least as much as the energy we used on earth is lost in the form of waste heat1. Thermoelectric (TE) power generators that enable the direct conversion from heat to electricity have been studied for a long time, much twethiavherilertirmyee,raaStlnh,lyadσ-n,daκtrbhitsvoeote(clnu...
[12] revealed that these transporters are members of a large phylogenetic subfamily of ABC transporters named Pdrp (for pleiotropic drug resistance proteins), where nuclear binding folds (NBF) alternate with domains comprising six predicted transmembrane spans (TMS) to form a NBF-TMS-NBF-TMS ...
To estimate the amount of blood mosquitoes consumed, 4-day post-emergence females were chilled and weighed in cohorts of ten using an analytical balance (Ohaus DV215CD). The average weight per individual NBF female was calculated from this value. Each cohort of ten was returned to a cage wit...