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Single-cell RNA sequencing (scRNA-seq) has revolutionized the transcriptomics field by advancing analyses from tissue-level to cell-level resolution. Despite the great advances in the development of computational methods for various steps of scRNA-seq an
Notably, the UG dinucleotide can combine with adenine to form either a start (AUG) or a stop (UGA) codon. Therefore, the UG dinucleotides in 5’UTRs are expected to be evolutionarily constrained. Also noteworthy is that the prevalence of CG methylation in gene body differs considerably ...
When mathematical modelling is applied to many different application areas, a common task is the estimation of states and parameters based on measurements. With this kind of inference making, uncertainties in the time when the measurements have been taken are often neglected, but especially in applic...
The FTE proportions of CSEs, major-form ASEs, and non-major-form ASEs are shown in Figure1a. When all exons are considered, inclusion level has a clear negative relationship with FTE proportion. Both the FTE proportions of major-form ASEs and non-major-form ASEs are significantly higher than...
Increased incidence of lung cancer among pulmonary tuberculosis patients suggests mycobacteria-induced tumorigenic response in the host. The alveolar epithelial cells, candidate cells that form lung adenocarcinoma, constitute a niche for mycobacterial re
The latter comes with variable amounts of indigestible animal tissues, such as raw bones, tendons, cartilage, skin, hair or feather. The undigested portion of the diet provides the main source of fermentable substrates for the intestinal microbiota, which form the main go-between in the ...
(HMT), N1-504, ofC. pasteurianumDSM 525, and ofC. beijerinckiiBAS/B3/I/124 and 59B were closed, all other genomes are draft form (Table1). The historical development of the sequenced industrial strains is depicted in Fig.1. Genome sizes vary between 4.099 Mb (C. acetobutylicumNCCB 24020...
Of the 15 nif genes, eight nif genes (nifB, nifH, nifD, nifK, nifE, nifN, nifX and nifV) and two non-nif genes (orf1 and hesA) form a complete nif gene cluster. In addition to the nif genes, there are nitrogenase-like genes, including two nifH-like genes and five pairs of ...
In the histogram the average log2 fold change is shown for 6 different genes, in response to the high effect concentration of phenanthrene (45.80 mg kg-1 soil). The genes used are from left to right: Fcc00508 (C-type lectin), Fcc00734 (UDP-glucosyltransferase), Fcc02784 (short-chain ...