Yang Xin Tang (YXT) is a traditional Chinese herbal preparation which has been reported to improve cognitive function and memory in patients with dementia. As the underlying mechanism of action of YXT has not been elucidated, we examined the effects of YXT and its major herbal components in reg...
orcortical reallocation(the two terms are equivalent and will be used interchangeably in the text) correspond to the experience-dependent dedication of a cerebral region to a cognitive function that does not typically map to this region in
In non-small cell lung cancer (NSCLC), naïve B cells have been shown to inhibit tumor growth [15]. However, the B-cell subtypes involved in MIBC and their functions are still not fully characterized. Tertiary lymphoid structures (TLSs) are organized aggregates of immune cells that form ...
Understanding the mechanistic effects of novel immunotherapy agents is critical to improving their successful clinical translation. These effects need to be studied in preclinical models that maintain the heterogenous tumor microenvironment (TME) and dys
Two reviewers (MJ and XY) independently screened the titles and abstracts for relevance based on the eligibility criteria. The full-text records of the articles that met the eligibility criteria were retrieved, screened, and extracted. Any discrepancies during the screening process were resolved by ...
The first is the ratio of public employment over total employment, which accounts for the size of the government sector as an employer. This variable is expected to correlate negatively with the public wage gap: a smaller public labor force is more likely to form an insider group of workers ...
During embryogenesis, the developmental potential of initially pluripotent cells becomes progressively restricted as they transit to lineage restricted states. The pluripotent cells of Xenopus blastula-stage embryos are an ideal syste
In Drosophila, mutations in the gene eyes absent (eya) lead to severe defects in eye development. The functions of its mammalian orthologs Eya1-4 are only partially understood and no mouse model exists for Eya3. Therefore, we characterized the phenotype of a new Eya3 knockout mouse mutant....
6a) shows a list of genes along with p-value, fold change and links to Gene Page in the form of tables. The Venn Diagram tab (Fig. 6b) visualizes overlapping of differential expression genes in different experimental conditions, and allows users to list and download all of genes name in...
In terms of considering aspects of reproductive/ children’s environmental health research in the “indirectness”, “heterogeneity”, or “confounding/ bias” domains, the Navigation Guide, GRADE approach, and OHAT framework all provide brief commentary, in the form of examples or general guidance,...