In addition, miR-142a-5p is an important regulator of denervation-induced skeletal muscle atrophy, which can induce mitochondrial dysfunction, mitophagy and apoptosis by targeting MFN1 [184]. Spinal cord injury is a unique form of disuse atrophy in which paralysis and disruption of the central ...
Because of the dangers of local delivery of drugs to the myocardium, the choice has been made to use TPP + in combination with the specific peptide CSTSMLKAC (PEP) to modify mitochondria, taking the form of an intravenous injection, where mitochondrial complexes in the bloodstream can be...
The hierarchical features of the last three layers of the search map X are fused through the multi-layer feature fusion module of the search branch (MFFMS), and the search map features are output in the form of f(X). 2. Self-attention network (see ‘Self-attention calculation’ section...
Social distancing hinders the human-to-human transmission of the coronavirus in the form of droplets from the mouth and nose, as evidenced by the report from Sun and Zhai [88]. Conversely, Nair & Selvaraj [89] demonstrated that social distancing was less effective in communities and cultures ...
including health, the web, postal services, etc. Images, video, sound, speech, and natural language can all be fed into CNN [38,39]. Convolution, pooling, Relu correction, and fully connected layers are all simply stacked together to form CNN (see Fig.7), which starts with a convolution...
BNIP3(#3769S), IL-6 (#12,912), IL-1β(#12,242), iNOS (#sc-7271), COX2 (#4842), p65 (#8242), Phospho-p65 (#3033), SOX9 (#A00177-2) were purchased form CST. MMP3 (#17873-1-AP), COL2 (#28459-1-AP), MMP13 (#18,165- 1-AP), SLC7A11 (#26864-1-AP), ...
Gasdermin (GSDM) family proteins, known as the executors of pyroptosis, undergo protease-mediated cleavage before inducing pyroptosis. We here discovered a form of pyroptosis mediated by full-length (FL) GSDME without proteolytic cleavage. Intense ultrav
The IMM folds inward to form cristae, increasing the surface area of the IMM and thus maximizing the function of mitochondria in synthesizing bioenergy [20]. Within the mitochondrial matrix, the enzymes connected to the tricarboxylic acid (TCA) cycle and fatty acid oxidation (FAO), as well as...
regulate the OXPHOS pathway [27,28]. When mtDNA replication is promoted by lineage-specific markers (vimentin, nestin, β-tubulin), upregulation of PolgA, PolgB, Tfam, ATPase5b, COXI is observed, and the organelle differentiates to an elongated form with swollen cristae to consume more oxygen...
INF2 inverted formin 2, JNK Jun N-terminal kinase, LC3 microtubule associated protein 1 light chain 3, LONP1 lon protease 1, MAPK mitogen-activated protein kinases, MARCH5 membrane associated ring-CH-type finger 5, MDV mitochondria derived vesicle, Met MET proto-oncogene, MFF mitochondrial fiss...