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Additionally, higher levels of proteins in ovarian cancer-derived exosomes that have diagnostic potential include CD24, CRABP2, MUC16, MSLN, soluble form of activated leukocyte cell adhesion molecule, and soluble E-cadherin [171, 177,178,179]. Levels of small heat shock proteins have also been...
Types of systematic reviews Full size image There are resources for those who are moving from the beginning stage and gaining more expertise (See Table 1). Cochrane conducts online interactive master classes on systematic reviews throughout the year and there are web tutorials in the form of e-...
Myelodysplastic syndrome (MDS) is a complicated hematopoietic malignancy characterized by bone marrow (BM) dysplasia with symptoms like anemia, neutropenia, or thrombocytopenia. MDS exhibits considerable heterogeneity in prognosis, with approximately 30% of patients progressing to acute myeloid leukemia (AML...
For example, excess growth of E. coli strain C25 increases gut permeability [11], spreading luminal content into the systemic circulation and triggering local and systemic immune response. Changes in intestinal microbiota in the form of increases in α-diversity and increase in the abundance of ...
There are several meta-analyses of randomized controlled trials (RCTs) demonstrating the benefits of virtual reality (VR) training as an intervention for motor performance, activity of daily living (ADL) and quality of life (QoL) outcomes in patients with Parkinson's disease (PD). However, the...
Maintenance of physical function, mobility, and independent living are important goals for older adults. However, concerns about falling (CaF) play a central role in the vicious cycle of CaF, inflammation, loss of muscle mass, and decreasing physical function ultimately resulting in negative health ...
Extracellular vesicles (EVs) have emerged as an exciting tool for targeted delivery of therapeutics for a wide range of diseases. As nano-scale membrane-bound particles derived from living cells, EVs possess inherent capabilities as carriers of biomolecu
Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder characterized by decreased platelet counts and an increased risk of bleeding. Multiple humoral and cellular immune abnormalities result in accelerated platelet destruction and
Geriatric rehabilitation is a multidisciplinary intervention that promotes functional recovery in older adults. Our objective was to assess the efficacy of geriatric rehabilitation in inpatient and geriatric day hospital settings. We searched MEDLINE, EM