在计算机辅助设计（CAD）技术的发展过程中，有两个重要的里程碑。CAD技术中的第一次重大创新发生在1963年，当时伊凡·萨瑟兰（Ivan Sutherland）在麻省理工学院（MIT）的博士论文中创建了Sketchpad，这是一个基于图形用户界面（GUI）的系统，用于生成x-y图。第二个里程碑是1971年由P.J. Haranty
Then a density-based regional clustering method is imposed on those true MCs to form MCCs. Finally, another DCNN is employed to differentiate benign from malignant MCC lesions. For cluster-based MCC detection evaluation, a sensitivity of 90% is achieved at 0.14 false positives (FPs) per image....
The plasmid pcDNA3.1-FLAG-HER2 was derived from pcDNA3.1-EF1a-mcs-3flag-CMV-EGFP and purchased form HANBIO (Shanghai). The full length of CMTM6 cDNA sequence was amplified by PCR using the cDNA of MDA-MB-231 cells as the template, and the primers of EcoRI-CMTM6-F (5′-CCCgaattcgG...
Software implementation and computational experiments and analysis were performed by AD, under the supervision of MCS. AD and MCS wrote this manuscript. All authors read and approved the final manuscript. Corresponding author Correspondence to Arun Das. ...
Plasmonic visible–near infrared photothermal activation of olefin metathesis enabling photoresponsive materials Introduction As the second-largest petrochemical after ethylene, propylene is widely used in many fields, especially in the form of polypropylene used in the medical field1,2. In industry, propyl...
Activation of mast cells (MCs) can be achieved by the high-affinity receptor for IgE (FcεRI) as well as by additional receptors such as the lipopolysaccharide (LPS) receptor and the receptor tyrosine kinase Kit (stem cell factor [SCF] receptor). Thus, pharmacological interventions which stabi...
Geobacter species in a phylogenetic cluster known as subsurface clade 1 are often the predominant microorganisms in subsurface environments in which Fe(III) reduction is the primary electron-accepting process. Geobacter bemidjiensis, a member of this cla
Proceedings of the First International Workshop on Multiple Classifier Systems, MCS ’00 London, UK: Springer-Verlag; 2000, 1–15. [http://link.springer.com/chapter/10.1007%2F3-540-45014-9_1] Chapter Google Scholar Johnson M, Zaretskaya I, Raytselis Y, Yuri Merezhuk SM, Madden TL:...
1a). The ability of single cells to form colonies is a way to measure cell self-renewal, a key feature of stem cells. Single cells from each of the three types of the AS cells generated colonies on day 14, likewise did BMSCs (Fig. 1b). Colony forming efficiency of the APCs (15....
Two NN architectures and one classical ML algorithm were used for the analysis. The two NNs differ primarily in the way the features were fed to the network input, as shown in Fig.3. In the single-input NN (sNN), gene expressions and drug descriptors were concatenated to form an input ...