FGS is a common consequence of schistosomiasis, a parasitic disease caused, in its urogenital form, by the trematode Schistosoma haematobium [10]. The deposition of schistosome’s eggs into urogenital tissue perpetuates inflammatory and proinflammatory responses leading to the formation of granulomas ...
The author developed a dual fixation method: initially, a high-strength suture was looped through the edge of the PCL’s tibial attachment and wrapped around the ligament to form a cuff. Subsequently, a button plate was positioned directly over the high-strength suture above the fracture block....
Overall, although significant progress has been made in the understanding of PF, the clinical management of PF remains unsatisfactory. However, the emergence of novel inhalation therapeutic techniques presents new opportunities for the treatment of PF, and they also bring certain challenges that require ...
The structure of CAR has been constantly updated (Fig.1). First-generation CAR consisted of an extracellular structural domain recognizing antigen and a single intracellular motif. Still, there were no costimulatory molecules in the structure, making it difficult for CAR-T cells to persist in patie...
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called viral enzymes, for a total of 16 non-structural proteins [3]. Subsequently, the non-structural proteins form a replication/transcription complex (RNA-dependent RNA polymerase), using the genomic RNA (+) as a model. The WHO clarified that there are a high number of mutations as more ...
The latter impairment is the most serious form of DNA damage [135]. A disfigured genome is the stimulus that initiates DNA damage response (DDR) processes [136,137]. These consist of a series of complex events that heal the DNA lesions. When the damage is highly deleterious, however, it ...
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The PayPal Local Payment Method Agreement is now called the PayPal Alternative Payment Methods Agreement. A Local Payment Method (LPM) is now called an Alternative Payment Method (APM). Corresponding changes have been made to other related terminology and to other agreements to reflect the new term...
Government retains a nonexclusive, paid up, irrevocable, worldwide license to publish or reproduce the published form of this work, or allow others to do so, for U.S. Government purposes. Competing interests The authors declare that they have no competing interests. Publisher’s Note Springer ...