transcription factors, which in turn interact with mediator complexes or other transcription co-activators to promote the recruitment of RNA Pol II and chromatin-modifying enzymes to the promoter region and form chromatin loop (enhancer-promoter loop) to foster the transcription of enhancer target ...
As outlined in the published protocol [16], a data abstraction form was developed and pilot-tested by two researchers working independently of each other. The abstracted data were synthesized according to three themes: study characteristics, population health characteristics, and human factors characteris...
ECE1 is a protease that cleaves big endothelin‐1 (ET1) into its active form, promoting vasoconstriction. The role of ECE1 in vasoregulation has been demonstrated in the blood vessels of the retina, optic nerve, and choroid [35]. In carcinoma cells and ventricular myocytes, downregulation of...
The complex interspersed pattern of segmental duplications in humans is responsible for rearrangements associated with neurodevelopmental disease, including the emergence of novel genes important in human brain evolution. We investigate the evolution of LCR16a, a putative driver of this phenomenon that encod...
[18F]LUF (Rf = 0.3) was stable in the mouse body and was present in mostly unchanged form in the plasma and heart. From the perspectives of reliability and quantitativeness of PET measurement, it is crucial that a PET tracer remains almost unchanged in the blood and target tissue. ...
The RCEP leaders meeting in 2020 was an important moment in RCEP negotiations. This meeting became the key venue for negotiating member countries to agree on final form of the agreement. Unlike in 2019, the 2020 sentiment score was positive for domestic and strategic issues, but the overall sen...
Moreover, brachytherapy with 125I seeds is considered an advanced form of low-dose radiotherapy, especially for the salvage treatment of recurrent cancer after external radiotherapy [20, 25]. Permanent interstitial 125I seed implantation offers the advantages of high precision, strong adaptability, and...
symptom-based), we assessed: (1) the number of pads used per day; (2) the subjective continence using the question “Do you suffer from incontinence? (yes/no)” and (3) continence via the German version of the International Consultation on Incontinence Questionnaire Short-Form (ICIQ-SF). ...
The research was approved as Clinical Trial 2020 (261) by the Ethics Committee of the Second Affiliated Hospital of Chongqing Medical University, and all subjects signed an informed consent form. Laboratory and imaging evaluation According to previous studies, risk factors affecting fatty liver were ...
As both forms of capital are present within any given family, the relative effects of either form of capital must be accounted for to understand the “true” and “unique” effects on different educational outcomes, net of socio-demographic controls. However, such comprehensive analyses have been...