MtDNAs are assembled with DNA-binding proteins such as TFAM to form mitochondrial nucleoid structures, and in live imaging, nucleoids dynamically move inside mitochondria and change their distribution and morphology. We previously reported that the dynamic features of nucleoids are regulated in cooperatio...
the steel bars of all specimens yielded. After yielding of steel reinforcement, the steel strains of group BA (reinforced concrete specimens) increase, even the load does not increase, indicating full but gradual collapse of test specimens. On the other hand, test specimens in group BD (reinforc...
The shisham tree (Dalbergia sissoo) is a keystone hardwood species of South Asia, highly valued in economic value in forestry, agroforestry, and landscape horticulture due to its durable, fragrant, and decay-resistant wood. However, shisham's health on b
transcription factors, which in turn interact with mediator complexes or other transcription co-activators to promote the recruitment of RNA Pol II and chromatin-modifying enzymes to the promoter region and form chromatin loop (enhancer-promoter loop) to foster the transcription of enhancer target ...
In fact, this allows us to exploit knowledge on μX in the form of informative priors and infer the dimensionless rates α,koff, and kon. These are converted to min−1 by using d~ estimated from data (Additional file 1: Section S5). In the limit as koff→∞,α→∞, with their ...
differentiation [45]. The KLRC2 protein (also: NKG2C) can bind to CD94 and HLA-E to form a functional complex [53], and thus, the depletion ofKLRC2is likely to have a significant impact on the development of severe COVID-19 [44]. In the visual cortex, microglial CD94/KLRC2 is ...
Lcr ranges from 0 to 1, while 0 means the variant passes the quality control of low coverage. 2. Variant allele frequency risk vafr=1−dmd (2) Where dm is the depth of the variant. 3. Near Head Rate nh=dhdm (3) dh is the number of supported reads whose distance ...
form Non-clinical (NC) isolates were enriched for genes associated with metal homeostasis and cadmium and copper resistance, likely linked to their addition to feed additives in the agricultural industry. Arredondo-Alonso et al. (2020) also found localisation of copper resistance operons to the ...
In their simplest form, cross-lagged panel models are made up of two constructs that are measured at two or more time points (Berry & Willoughby, Citation2017; Selig & Little, Citation2012). These time points are ideally spaced apart such that a temporal sequence of cause and effect can be...
The complex interspersed pattern of segmental duplications in humans is responsible for rearrangements associated with neurodevelopmental disease, including the emergence of novel genes important in human brain evolution. We investigate the evolution of LCR16a, a putative driver of this phenomenon that encod...