Deoxyribonucleic acid (DNA) methylation is one of the epigenetic modifications that has gained a lot of interest as a factor influencing fetal programming and as a biomarker for adverse pregnancy and birth outcomes (APBOs). Epidemiological studies have d
The study was conceptualized by JPT and NDN. NDN and LWB provided oversight and mentorship. The methodology was developed and revised by JPT, DPI, JBB, JTD, PG, SJK, PS, NKW, CLS, LWB, and NDN. Resources for developing and carrying out the protocol were provided by JBB, SJK, PS, NKW...
MiRNA expression profiling is being actively investigated as a clinical biomarker and diagnostic tool to detect multiple cancer types and stages as well as other complex diseases. Initial investigations, however, have not comprehensively taken into accou
Infection of plants by viruses interferes with expression and subcellular localization of plant proteins. Potyviruses comprise the largest and most economically damaging group of plant-infecting RNA viruses. In virus-infected cells, at least two potyvira
There is some evidence to suggest that animal-assisted interventions can have beneficial impact for residents in long-term care, but the focus of the evidence has largely been on behavioural and psychosocial measured outcomes. Animals, either as companion animals or in the form of pet/animal-assis...
ant is unable to sign or make a mark on the consent form, verbal consent will be obtained that will be witnessed by an independent observer (staff member, relative or friend). If recruitment is conducted remotely, verbal consent will be obtained and will be documented on the consent form....
Data continue to accumulate indicating that many systematic reviews are methodologically flawed, biased, redundant, or uninformative. Some improvements have occurred in recent years based on empirical methods research and standardization of appraisal too
Taping is increasingly used to manage proprioceptive deficits, but existing reviews on its impact have shortcomings. To accurately assess the effects of taping, a separate meta-analyses for different population groups and tape types is needed. Therefore, both between- and within-group meta-analyses ...
is the most common form of neurodegenerative dementia affecting nearly 50 million people worldwide with higher incidence rates as age increases [1]. among various described genetic risk factors [2], the ε4 allele of theapoegene (apoeε4) confers the strongest genetic risk to develop ad and ...
[5]. However, children who are not stunted according to this definition can still be short for their age and suffer from growth faltering [2]. Stunting reflects chronic undernutrition [6] and is the most common form of malnutrition in children under 5 [1,2,3]. Other forms of ...