The spatial domains detected by SpaDo form a multi-resolution schema hierarchically, enabling the characterization of spatial structures dynamically with different resolutions. In order to distinguish the spatial domains under different resolutions, we adopt the following naming scheme for the spatial domain...
In recent decades, the prevalence of metabolic diseases, particularly diabetes, hyperlipidemia, obesity, and non-alcoholic fatty liver disease (NAFLD), has increased dramatically, causing great public health and economic burdens worldwide. Traditional Ch
Understanding which factors of globalization (i.e., social, economic, or political) have influenced government public health responses (in the form of travel/border restriction policies) during COVID-19 can help identify useful global coordination mechanisms for future pandemics, and also improve the...
The resolution of genome binning though, is limited by the resolution of the assembler, with a typical maximum kmer length of around 100, the best case is that we can resolve to about 1% sequence divergence, so that bins correspond to something between a species and a strain. In the presen...
In total, ePKs account for 2.0% of total P. infestans genes, which compares to 1.3 to 6.6% for the other eukaryotes in Table 1. Details of each family in P. infestans are presented in later sections, except for receptor guanylyl cyclase (RGC) kinases which were not detected and are ...
aggregated ESM, orαESM for short, exhibits an accurate performance prediction combined with a closed-form solution, enabling a flexible LA strategy, that selects at every protocol round the MCS maximizing the expected goodput (EGP), i.e., the number of correctly received bits per unit of ...
Current ligand-based machine learning methods in virtual screening rely heavily on molecular fingerprinting for preprocessing, i.e., explicit description of ligands’ structural and physicochemical properties in a vectorized form. Of particular importance to current methods are the extent to which molecular...
suggests they may form from near-surface chloride and sulfate salt brines [14]. Geomorphological features resembling gullies formed in the recent geologic past [15] are suggested to have formed from subsurface eutectic brines [16]. Thus, the GH springs provide a useful analog for examining ...
already suggest that they form developmental modules during ontogeny. At a macroevolutionary scale, these developmental modules could act as evolutionary units of change and contribute to the disparity in fin configurations. This study addresses fin disparity in a phylogenetic perspective, while focusing ...
of genes differentially expressed between genders and between developmental stages that suggest a role involved in sex differentiation. Also, the detection of differentially transcribed regions that extended existing gene models (intergenic regions) between sexes suggests that they may account for some of ...