Microsatellite instability (MSI) is a form of hypermutation caused by defects in the mismatch repair mechanism. MSI algorithm was used to evaluate the relationship with immune response. From the LIHC_GSE98638 dataset, approximately 5059 high-quality cells were filtered and retrieved. Tumor Immune ...
Conversely, while carboxydovores may oxidise high concentrations of CO they can also oxidise atmospheric levels but only benefit from this reaction by acquiring energy in the form of electrons coupled to ATP generation [1, 3]. The physiology, biochemistry, and genetics of carboxydotrophs have ...
These diversified marine functional zones form a subtropical coastal continuum with multiple environmental gradients (Fig. S1), serving as a model to explore biogeographic patterns of microbial co-occurrence features across complex environmental gradients. In this study, using an integrated 16S/18S rRNA ...
The Short Form-36 survey (SF-36) assesses the health-related quality of life (HRQoL) of individuals based on 36 items. It measures eight health domains: physical functioning, role limitation due to physical problems, bodily pain, general health perception, vitality, social functioning, role limit...
The pellets were then resuspended to form bacterial suspensions, which were diluted to an OD600 of 2.0. The OD600 of each bacterial suspension was adjusted to a proper concentration, ensuring that the final optical density of the mixed SynCom was 10 [7] cells per gram of soil [25]. Microbe...
Bacterial communities are crucial components of various ecosystems, significantly contributing to the flow of energy and materials on the planet [1, 2]. They are present in diverse environments, such as the human body, where they form the microbiome—a determining factor in our health. A major ...
A range of interventions have been implemented globally to address malnutrition, ranging from micronutrient supplementation programmes (where single micronutrients in the form of injections, formulas or tablets are administered to an individual), to food-based interventions (where nutrient deficiencies are ...
The Haitian and Dominican Republic isolates form a tight cluster, with only four variants unique to individual isolates. These variants are located in the CTX region, the SXT region, and the core genome. Of the 126 mutations identified that separate the Haiti-Dominican Republic cluster from the ...
(the salt form of the acid in solution) presented with little antimicrobial activity in isolation, but when combined with amoxicillin, it significantly lowered amoxicillin MICs againstStaphylococcus aureus,Klebsiella pneumoniae,Proteus mirabilisandE. coli[16]. Sulbactam and tazobactam are penicillinate ...
Anaerobic digestion (AD) of organic waste is considered to be a sustainable waste treatment practice, as it reclaims potential energy from waste in the form of biogas and provides a route by which nutrients can be recycled back to land [...