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It has also been suggested that autolysin can weaken the peptidoglycan layer of bacteria, causing the inner membrane to protrude into the peripheral space and form OIMVs, which contain cytoplasmic contents [50]. Furthermore, recent studies have identified novel Gram-negative extracellular vesicles. ...
In Brazil, the official frequency of relapses after VL treatment among non HIV-infected patients is underestimated, although the compulsory notification form has a specific field to inform this clinical presentation [25]. In the literature, the vast majority of studies are related to therapeutic fai...
Invasive aspergillosis (IA) is a major cause of infectious morbidity and mortality in immune compromised patients. Studies on the pathogenesis of IA have been limited by the difficulty to monitor disease progression in real-time. For real-time monitoring
10.1128/IAI.00477-06. Article PubMed Central CAS PubMed Google Scholar Giammarinaro P, Paton JC: Role of RegM, a homologue of the catabolite repressor protein CcpA, in the virulence of Streptococcus pneumoniae. Infect Immun. 2002, 70 (10): 5454-5461. 10.1128/IAI.70.10.5454-5461.2002. ...
MEGAN, however, can only compare single pairs of metagenomes, as is also the case with STAMP [37], which does introduce a concept of 'biological relevance' in the form of confidence intervals. UniFrac [38] compares sets of metagenomes at a strictly taxonomic level using phylogenetic distance...
Our previous studies revealed that a new disease form of streptococcal toxic shock syndrome (STSS) is associated with specific Streptococcus suis serotype 2 (SS2) strains. To achieve a better understanding of the pathogenicity and evolution of SS2 at the whole-genome level, comparative genomic anal...
Altogether, this resulted in a total of 6,495 genes, which form the basis for the present study (Additional file 1: Table S1, sheet “Summary”). We used the respective predicted amino acid sequences to perform a number of bioinformatic analyses to characterize the proteome of Bgh DH14. ...
Secondary outcome measures included the American Shoulder and Elbow Surgeons (ASES) shoulder assessment form and a count of revisions required in each group. Outcome measures were completed preoperatively and at three, six, twelve, eighteen, and twenty-four months after surgery. WORC and ASES ...
Together, these studies form a wide body of evidence that supports the potential role for Mycobacteria in CD. However, an incomplete understanding of the cellular mechanisms responsible for the pathology of colitis makes this conclusion uncertain. There is a consensus that the mucosa of CD patients...