If the known data form an incomplete bi-clique, the incomplete relations in the bi-cliques to be identified as predicted links between drugs and diseases. Ye integrated known drug target information and proposed a disease-oriented strategy for evaluating the relationships between drugs and a ...
LC3-I (18 kDa) is cytosolic and LC3-II (16 kDa) is the lipidated form (conjugated to phosphatidylethanolamine) that inserts into the membrane. The amount of LC3-II is correlated with the extent of autophagosome formation and increasing levels of LC3-II on immunoblots have been used to ...
As a kind of strong polar molecule, carboxyl groups (–COOH) combine with water molecules by the van der Waals force, and meanwhile, the water molecules connect each other by hydrogen bonds interaction to form clusters to induce continuous adsorption on the surface of the PI membrane. However,...
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B16 melanoma cells cannot form tumors in allogeneic mice unless co-injected with MSCs [26]. When human breast cancer cells mixed with bone marrow-derived human MSCs were injected in a mouse model, there was a higher speed of metastases [27]. On the other hand, there are also many reports...
it had a higher standard than was otherwise so common in the GDR and even in retrospect, the coal industry solved all the problems. There was no broad middle-class industry like in West Germany, where there are several companies that form the economic backbone of the region, and then people...
Phosphatidylcholine (PPC) formulation is used for lipolytic injection, even though its mechanism of action is not well understood. The viability of 3T3-L1 pre-adipocytes and differentiated 3T3-L1 cells was measured after treatment of PPC alone, its vehic
To address major threats to the sustainability and quality of life in urban settings, many municipalities have started exploring routes toward smarter cities to, for example, lower their energy consumption and carbon footprint. These explorations, in the form of living labs or other pilot projects,...
vaccines Review Novel Protein-Based Pneumococcal Vaccines: Assessing the Use of Distinct Protein Fragments Instead of Full-Length Proteins as Vaccine Antigens Theano Lagousi 1,*, Paraskevi Basdeki 1, John Routsias 2 and Vana Spoulou 1 1 First Department of Paediatrics, "Aghia Sophia" Children's...