Form and function: MACC1 structure determines its interactions The structure of MACC1 is well characterized, consisting of 852 amino acids, with an N-terminal intrinsic disorder region followed by a ZU5, a SRC Homology 3 (SH3), and double-death domains close to the C-terminus [4, 5, 49...
Finally, the accumulation of adverse political, economic and social effects brought about by oil extraction at local level can create grievances that lead to armed conflict [15]. A typical example is the ongoing political violence in the Niger Delta region [56]. As a particular form of armed ...
Air pollutants comprise a mixture of gases, organic compounds, metals and particles [17]. Within this mixture, fine particulate matter (PM2.5) is the pollutant with the strongest relationship with negative health outcomes and mortality [18, 19]. The process of fossil fuel combustion is the main...
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Tumor cellular metabolism exhibits distinguishing features that collectively enhance biomass synthesis while maintaining redox balance and cellular homeostasis. These attributes reflect the complex interactions between cell-intrinsic factors such as geno
Maternal tobacco smoke is a personalized form of air pollution for the mother herself and fetus [73]. Although smoking is controllable, more than half of female smokers continue to smoke after pregnancy [81]. In utero exposure to smoking is associated with alterations of DNA methylation patterns...
Hsd:Sprague Dawley®™SD®™female and male rats of an outbred strain (Harlan, Indianapolis, IN, USA) were maintained inventilated (up to 50 air exchanges per hour) isolator cages containing Aspen Sani chips (pinewoodshavings from Harlan) as bedding, on a 14 h light: 10 h dark ...
2c, d; Additional file 1), but abiotic stress in the form of frost damage was moderately influenced by position in the field (r 2 = 0.385; Table 2). Fig. 2 Thin-plate spline correction models. a Scatter plot of the total height values predicted by the model versus the observed ...
form stable dinitrophenyl hydrozone adducts. Derivatized proteins were precipitated with trichloroacetic acid and were washed three times with acetone. The samples were resuspended in 100 μl of 6 M guanidine (pH 2.3). Protein oxidation, expressed as nanomoles of carbonyl groups per milligram of ...
Testicular enzymes such as delta 5, 3 beta-HSD, 17 beta-HSD, and sorbitol dehydrogenase (SDH) were significantly decreased, but those of acid phosphatase (ACP), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) were significantly increased. A decrease in dopamine or an increase in ...