In addition, the linearly close genes have a higher probability of co-expression and their protein products tend to form protein–protein interactions. However, the organization features of bacterial genomes in a three-dimensional space remain elusive. The DNA interaction data of Escherichia coli, ...
Natural language processing (NLP) is a theoretically motivated range of computational techniques for the automatic analysis and representation of human language [1]. Its goal is to realize human-like language understanding for a wide range of applications and tasks [2]. As a large and complex dom...
When appropriate, the Aβ monomer is purified on a C18 column (SPE-Chromabond-HRX C18 ec, 200 μl, 5 mg, Macherey-Nagel, France). The column was equilibrated with 0.1% trifluoroacetic acid (TFA) in water. Immediately after dilution in DMSO, the Aβ sample was loaded and the column was...
Ubiquitinated H2B (uH2B) stimulates the activity of most KMT2s [28] (Fig.1). Only KMT2G does not require uH2B to form H3K4me3 in an in vitro reconstituted chromatin system [28] (Table1). Our group has previously shown that the ubiquitination of H2B is dependent on transcription [29]. ...
(data not shown). Several proteins in other SET families are also found in closely related pairs: EZH1 and EZH2 (members of the EZ family), MLL1 (also called HRX) and MLL2 (HRX2, both members of the SET1 family), SET1 and SET1L (SET1 family), NSD2 (WHSC1) and NSD3 (WHSC1...