Gene fusion refers to a sequence in which some or all of the sequences of two genes are fused through some mechanism (such as genome variation) to form a new gene [50, 51]. A fusion gene can induce the production of SEs, thereby driving the transcription of oncogenes. Benbarche et a...
Microbial colonization in the plant rhizosphere can endow the host with various biological functions. For example, nitrogen-fixing rhizobia can form symbiotic nodules to provide a nitrogen source for the growth of leguminous hosts, which represents the highest level of mutual benefit between host plant...
In vitro analyses of HTLV-I-infected cells revealed that HTLV-I-infected cells form "virological synapses" with uninfected cells. Contact between an infected cell and a target cell induces the accumulation of the viral proteins Gag and Env, viral RNA and microtubules, and the viral complex ...
which is a key factor of cell functions, emphasizing its regulatory roles in DNA replication and participation in DNA repair. Additionally, HBO1’s involvement in ubiquitination, where it can be ubiquitinated itself and also acts as a ubiquitin ligase, is explored. The crucial role of HBO1 ...
aonce a form of legal tender 法定看护人的一次形式[translate] acentral tenet 中央原则[translate] ais switch to 是开关[translate] aCompetition is not blind, need to have the backing of core resources. Competition in the mature and fully, making what is not so easy. Can not be easily revers...
interacts and heterodimerizes with MafB via each bZIP domain. HBZ abrogates the Maf recognition element (MARE) binding activity of MafB and reduces steady-state MafB levels [109]. Therefore, interactive partners also play an indispensable role in the target gene expression of large Mafs in the pr...
(ATLL), significant collaboration between viral and cellular TFs has been documented in SE development. Mechanistically, the HTLV-I-encoded essential TF, HBZ, has the capability to interact with the SE domain ofBATF3, thus initiating the transcription of BATF3 and its downstream targets, which ...
(an overdispersed poisson),approximated by a normal in large regions. this form is based on studies that have found that the distribution of fragments along the reference genome has greater variation than a poisson distribution [ 46 ], and is biased by the gc content of the fragment [ 46 ...
(HCV). The causal contribution of the above-mentioned viruses to the development of human neoplasms is now well documented. Besides these, there are other viruses with a potential influence on human carcinogenesis. Recently, an integrated form of a new polyomavirus, MCPyV, has been detected in ...
these mechanisms may be associated with p30-mediated inhibition of G1/S progression, the active form of CDK2 bound to cyclin E was detected by immuno-precipitation of cyclin E from protein extracts of cells transfected with cyclin E-myc and CDK2-HA in the presence or the absence of p30-...