The first step is driven by membrane tension, allowing the local swellings to form on the tubular retraction fibers, and then the second step is controlled by specific proteins of the TSPAN family, which make TSPAN-based membrane domains stabilize these swellings that finally turn into migrasome...
A universal redux version of my Meteor attempt at Words with Friends (online scrabble). - words-with-strangers-redux/input_words.txt at master · joshwcomeau/words-with-strangers-redux
While CHMP2B-ΔC shows a homogenous binding to the GUV (Fig.1a, first panel), the interaction of MBP-CHMP2A-ΔC is rather weak under the same conditions (Fig.1a, third panel). Although MBP cleavage increases the interaction, it also induces aggregation of CHMP2A-ΔC in solution and o...
Two-dimensional (2D) MXenes with a general structure of Mn+1XnTx, where n = 1–4, are the derivatives of their corresponding three-dimensional (3D) bulk layered materials called MAX (or Mn+1AXn) phases. After chemical etching of A atomic layers from MAX, these compacted 3D structure...
During HIV particle assembly or soon after particle release, protease (PR, not shown) cleaves the Gag polyprotein to MA, CA and NC and protein rearrangement occurs to form the mature virion. (B) Close-up view of the HIV budding process. ESCRT-I is recruited to the budding site via ...
[12,13]. In the hepatocytes, the sporozoites evolve a mature form known as liver schizonts. These schizonts undergo mitosis to produce exo-erythrocytic merozoites (tissue schizogony or liver stage) [11]. Following replication within hepatocytes, mature merozoites are released into the blood ...
In vitro experiments with Giant Unilamellar Vesicles (GUV) model membranes have demonstrated that the I-BAR domain can oligomerise and deform membranes to generate actin-free ‘protrusions’ of a defined length and width in the absence of actin22 (‘protrusions’ will be used throughout the ...
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Membrane segmentation could be used to take an equal-thickness sampling of pixels around the GUV, for consistency of analysis across a population of multiple GUVs. Vesicles derived from cell membranes (GPMVs) and labelled with Laurdan (Fig. 2g) or Di-4-ANEPPDHQ (Fig. 2h) also exhibit ...
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