Beyond mechanisms for public domain reporting and oversight by mandated national audit and parliamentary bodies, ongoing debates also need to address the risk of corruption in pandemic financing, whether in the form of bribes, embezzlement, fraudulent contracts, inflated pricing, insider trading or diver...
This partitioning enabled the quantification of gene and genetic variation densities within each block. Employing an in-house Python script alongside a gene feature format (GFF) file and a variant call format (VCF) file, the gene and variant counts were computed for each respective block. To ...
2g). Similarly, full-length coverage with Smart-seq3xpress resulted in significantly (2–5-fold) increased read support over exon–exon and exon–intron splice junctions, which form the basis for RNA velocity inference16 (Fig. 2h). To perform a direct comparison of cluster granularity, we ...
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ligniperda and 12 other insect species, we employed a set of 1630 homologous genes. H. ligniperda and the other nine Curculionoidea insects clustered together to form sister relationships. Among them, H. ligniperda was highly related to D. ponderosae, and relatively distant from Anoplophora gla...
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TR catalyses the reduction of reactive oxygen radical superoxide anion to hydrogen peroxide and is responsible for maintaining the glutathione orthologue trypanothione in its reduced form, essential for redox defence systems in trypanosomatids. For this reason, TR would be a useful chemotherapeutic target...
3D). During later stages in control eyes, lens epithelial and lens fiber cells located inside the lens vesicle were EdU + at 10 dpl and 15 dpl respectively, whereas in clodronate liposome treated eyes, a lens vesicle failed to form, and EdU + cells were detected inside the iris ...
Genomic regions that displayed signatures of selection or suggestive signatures of selection were annotated with the Bedtools v.2.17 (https://bedtools.readthedocs.io/ [38]) by retrieving annotated protein coding genes from the OryCun2.0 NCBI’s GFF file. The functional relevance of the genes anno...
[68] were used to generate a modified GFF file for a genome, and alternatively spliced transcripts were filtered out. Subsequently, Diamond (version 2.1.6–1) [69] was used for performing protein–protein BLAST (e-value ≤ 1e−5), and the results were formatted in fmt6.blast. ...