Telomeres are regions of repetitive DNA at the ends of linear chromosomes which protect chromosome ends from degradation. Telomere lengths have been extensively studied in the context of aging and disease, though most studies use average telomere lengths
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However, even in this well-known case the precise mechanism of action of TBT in gastropods has not been fully determined, the regulatory implication of which is reviewed in Lagadic et al. [14]. The effects of TBT on other invertebrate phyla, at concentrations lower than those causing imposex...
[1] outlines several considerations, which might form the basis of future principles of Green Toxicology, the basis of which are: (1) benign-by-design (also known as safety-by-design); (2) test early—produce safe; (3) avoid exposure and thus testing needs; and (4) make testing sustai...
(localisation within membrane; STX1B & LRP4). Amphioxus myogenesis undergoes a unique form of innervation during muscle growth, whereby nerve attachments form from the myotomal muscle fibres and grow to connect with the neural tube [147.,148]. While the physiology of this process is somewhat ...
NEP is a membrane-anchored zinc-dependent endopeptidase, being able to cleave both Aβ monomers and oligomers. The role of NEP in the pathogenesis of AD is indicated by its decreased expression in the AD brain, particularly in vulnerable regions such as the hippocampus and the midtemporal gyrus...
cytoplasm) in the unstimulated cell. When PMN are stimulated, the cytosolic elements translocate to the plasma or phagosomal membrane where they associate with the membrane-bound flavocytochrome b558 to form a functional oxidase complex. Simultaneously the intracellular granules fuse with the phagosomal ...
Acute myeloid leukemia (AML) is the second most common form of leukemia in children. Aberrant DNA methylation patterns are a characteristic feature in various tumors, including AML. Metallothionein III (MT3) is a tumor suppresser reported to show promoter hypermethylated in various cancers. However...
The introduction of a simple and versatile near full genome amplification, sequencing, and cloning method enables broad application in phylogenetic studies of diverse HIV-1 subtypes and can contribute to personalized HIV therapy and diagnosis. Viruses 2019, 11, 317; doi:10.3390/v11040317 www.mdpi....
Sci. Nat. Form. 2021, 21, 45–60. Sustainability 2022, 14, 13883 14 of 14 36. Abdelzaher, M. Experiential investigation on the effect of heavy fuel oil substitution by high sulfur petcoke on the physico- mechanical features and microstructure of white cement composites. Eng. Res. Express ...