and neurological complications such as acute myelitis [87], and meningoencephalitis [88]. Microcephaly is a prenatal condition characterized by underdeveloped brain growth, leading to reduced head size in affected infants, while GBS manifests as muscle weakness stemming from immune-mediated harm to th...
HMGB1 can also bind to C-X-C motif chemokine ligand 12 (CXCL12) to form a heterocomplex, which induces monocyte recruitment via C-X-C motif chemokine receptor 4 (CXCR4) [48]. However, the function and regulatory mechanisms of HMGB3, which has a similar structure to HMGB1 and HMGB2, ...
COVID-19 patients manifesting neurological disorders one week prior and up to six weeks after infection were recruited from all the neurology centres of the government hospitals in Sri Lanka from May 2021 – May 2022. Data was collected using a structured data form that was electronically transmitt...
transcription factors, which in turn interact with mediator complexes or other transcription co-activators to promote the recruitment of RNA Pol II and chromatin-modifying enzymes to the promoter region and form chromatin loop (enhancer-promoter loop) to foster the transcription of enhancer target ...
European Journal of Medical Research 2017, 22(Suppl 1):S5 Linear growth failure in childhood is the most prevalent form of undernutrition globally. An estimated 165 million children under 5 years of age are stunted, with a height-for-age Z-score (HAZ) below − 2. It has now been recogn...
They utilized Diversity Arrays Technology (DArT) markers for genotyping, which were recorded in the form of presence (1) or absence (0) [32]. To ensure data quality, markers with minor allele frequencies less than 0.05 were removed. After quality control, the data contained 1279 markers. The...
HIV infection can contaminate semen at any stage [89], existing in the form of both free viral particles and infected cells [90]. There may be genetic variations in viral RNA and DNA sequences in semen during acute and chronic infection, indicating independent viral replication in semen [91]...
Nowadays, obesity is one of the largest public health problems worldwide. In the last few decades, there has been a marked increase in the obesity epidemic and its related comorbidities. Worldwide, more than 2.2 billion people (33%) are affected by overw
To reduce duplicate functional genes in SMGC and GMGC, these predicted genes were clustered at the protein level using the UniRef model [58] at 100% and 90% amino acid identity to form SMGC100, SMGC90, GMGC100, and GMGC90, respectively. A total of 57.4% and 47.8% known proteins in ...
The form of shear fracture was directly related to the state of the near-interface matrix on the TA1 side. At the same time, the stress change during the tension-shear process also caused the near-interface matrix to participate in shear deformation to a greater extent. Therefore, fine-...