but without a local spatial linkage between the two (Fig.1c). This is the case for many inverse problems. The transform between the two domains may take the form of an integral
After signing a research consent form the patients were evaluated by two clinical geneticists (MW and FP) who collected the clinical data (including the self-report questionnaires to evaluate NMS of PD) and assessed for the presence of parkinsonian manifestations. Motor symptoms of PD were assessed...
KRAS can promote the accumulation of succinate in the form of α-KG in a SLC25A22 (a mitochondrial glutamate carrier that mediates glutamine catabolism)-dependent manner. This mechanism promoted DNA methylation, caused activation of β-catenin and increased expression of LGR5 as well as augmented ...
FBP-interacting repressor (FIR) was an inhibitor of FUBP1 and was demonstrated to inhibit the interaction between FUBP1 with c-myc promoter [25]. Meanwhile, previous studies reported that long non-coding RNA (lncRNA) or circRNA could inhibit the interaction between FUBP1 and FIR to promote c...
Based on this, MMAF may be another form of classical PCD [6]. Second, according to animal models, the process of flagella formation is not identical to that of cilia. For instance, the Bbs4-null mouse model failed to form sperm flagella, but developed primary cilia in other organs ...
[2,3,4]. It is capable of accumulating high levels of internal storage lipids in the form of triacylglycerols (TAGs) from excess carbon when other nutrients such as nitrogen, phosphorous or sulphur are limited [5,6,7]. Its natural capacity to grow on a variety of carbon sources, ...
Isolated rapid eye movement sleep behavior disorder (iRBD) serves as a prodromal phase of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Blunted tachycardia (BT) during postural changes indicates neurogenic orthostatic hypotension, a mark
purpureum, but the chromophore under ND was much smaller, just about a third of the size of the CK cells. However, cell size did not significantly change in either conditions. Intracellular polysaccharides aggregated in the form of ‘starch granules’, which significantly accumulated in ND cells....
such as lipid layer from the viscera in the form of fish oil extract in the extraction vessel. The Sc-CO2and fish oil extract complex (Sc-CO2 + fish oil extract) is then rapidly depressurized by the metering valve (No. 15) to reduce the pressure of CO2before being emitted to the...
Dendrimers form a distinct class of polymers with a branched three-dimensional structure, providing high adaptability. They are NPs with an unimolecular micellar structure featuring a hydrophobic core and a hydrophilic outer layer. Similarly, polymeric micelles are characterized by their amphiphilic ...