Circular RNA Itchy E3 ubiquitin protein ligase (Circ-ITCH) is significantly down-regulated in various kinds of tumors, however, the mechanisms of action and functions of circITCH gene in prostate cancer (PC) are still under investigation. The mail goal of this research was to study the function...
Despite considerable advances in malaria medicines in the past 20 years, the global burden of malaria remains substantial. Moreover, continued emergence of drug resistance ensures that new antimalarials will be needed in the near future. Wells and collea
β-catenin is a key mediator of the canonical Wnt pathway as it associates with members of the T-cell factor (TCF) family at Wnt-responsive promoters to drive the transcription of Wnt target genes. Recently, we showed that Rac1 GTPase synergizes with β-
Deep eutectic solvents (DESs) are eutectic mixtures of salts and hydrogen bond donors with melting points low enough to be used as solvents. DESs have proved to be a good alternative to traditional organic solvents and ionic liquids (ILs) in many biocata
Gap models are individual-based models for forests. They simulate dynamic multispecies assemblages over multiple tree-generations and predict forest responses to altered environmental conditions. Their development emphases designation of the significant
Parkinson’s disease (PD), the second most common neurodegenerative disease worldwide, is caused by the loss of dopaminergic (DAergic) neurons in the substantia nigra resulting in a series of motor or non-motor disorders. Current treatment methods are unable to stop the progression of PD and ...
2r−edcostnrduucctutirvee, layers along the c-axis of the tetragonal favorable transport properties of carri- ers and tunable powdered form nwaerrreowprebpaanrdedga(ps,eBe iM1−extLhaoxCdsu)SteoOtessatmthpeliers with different compositions (x = 0, 0.04 and 0.08) in potential ...
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. The development of this malignant glial lesion involves a multi-faceted process that results in a loss of genetic or epigenetic gene control, un-regulated cell growth, and im
Autochthonous NOM is produced by microbial processes in the water. NOM concentration, composition and chemistry can exhibit significant variations in nature and are a function of temperature, pH and ionic strength, as well as photolytic and microbial processes [4]. There are literally thousands of ...
[95]. Gelatin NPs exhibited a prolonged release of EGCG, in contrast to non-coated NPs. The encapsulated form of EGCG retained its potency, effectively inhibiting the hepatocyte growth factor (HGF) and the resulting activation of cell signaling pathways that contribute to cell invasion in MDA-MD...