Pancreatic β cells differentiated from stem cells provide promise for cell replacement therapy of diabetes. Human pluripotent stem cells could be differentiated into definitive endoderm, followed by pancreatic progenitors, and then subjected to endocrin
3c). Taking the negatively charged wall of the microchannel as an example, when the liquid contacts the negatively charged wall of the microchannel, the cations in the liquid gather on the wall of the microchannel to form a thin electric double layer (EDL) (0.1 nm-10 nm). Under the ...
In recent years, increasingly more non-coding RNAs have been detected with the development of high-throughput sequencing technology, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), small nucleolar RNAs (snoRNAs), and piwi-interacting RNA (piRNAs). The disco...
so that additive binding of the required TFs could progressively overcome the higher propensity of the enhancers to form nucleosomes, allowing desired gene regulation. From the perspective of cellular phenotypic diversity, a given enhancer can regulate a cognate gene in multiple cell types differentially...
Subsequently, p-type-doped GaN with Mg is coated on the outside of the MQW to form a capping film. The structure and preparation process are shown in Figure 19a. The emission wavelength of the core/shell GaN nanowire LED is controlled by an external voltage, just like a multi-active QW...
The transcription factor Pax8 is essential for the differentiation of thyroid cells. However, there are few data on genes transcriptionally regulated by Pax8 other than thyroid-related genes. To better understand the role of Pax8 in the biology of thyroi
Here we describe the following accomplishments, which form the foundations of the ongoing SoNG Initiative: 1) three generations in the development of an evolving catalog of gene sequences expressed in the zebra finch brain; 2) production and validation of DNA microarrays useful for study of ...
The T-cell receptor (TCR), located on the surface of T cells, is responsible for the recognition of the antigen-major histocompatibility complex, leading to the initiation of an inflammatory response. Analysing the TCR repertoire may help to gain a bette
The field of microbiome research has evolved rapidly over the past few decades and has become a topic of great scientific and public interest. As a result of this rapid growth in interest covering different fields, we are lacking a clear commonly agreed
Excessive accumulation of lipids in the adipose tissue is a major problem in the present-day broiler industry. However, few studies have analyzed the expression of adipose tissue genes that are involved in pathways and mechanisms leading to adiposity in chickens. Gene expression profiling of chicken...