Notably, research on DPSC-EVs has provided solid evidence supporting their role in pulp regeneration. DSC-EVs hold considerable promise as tools for PDL regeneration by leveraging their immunomodulatory properties to counteract the excessive immune response typical of the periodontitis environment, promoting...
They embedded exosomes isolated from human dental pulp stem cells (hDPSCs) directly into HPCH/CW pre-gel to form exosome-loaded hydrogels (HPCH/CW/Exo), and experiments demonstrated that the delivery of exosomes significantly enhanced the hydrogel’s ability to promote pulp regeneration and ...
Firstly, under the influence of different cell types and stimuli factors, the cell membrane forms inward protrusions of varying shapes and sizes through "inverted budding." Subsequently, these protrusions gradually expand and detach from the parent cell membrane to form early endosomes [37]. Then,...
Cell therapy has emerged as a revolutionary tool to repair damaged tissues by restoration of an adequate vasculature. Dental Pulp stem cells (DPSC), due to their easy biological access, ex vivo properties, and ability to support angiogenesis have been la
If any of the RInChI layers are empty, they produce the string “UHFFFADPSC”. The next components are three groups of five letters, which are generated from the total protonation states and the minor InChI layers of RInChI layers two, three and four. The first letter of each group ...
which form dentin and bone responding to specific cytokines or growth factors [8,9,10]. One study revealed that DPSCs could differentiate into odontoblast-like cells capable of secreting mineralized dentin-like matrix [11]. Furthermore, Laino et al. discovered that the contact of DPSCs with the...
An estimated 50% of the world's adult population is affected by periodontitis in its mildest form, and the incidence increases to more than 60% in people over 65 years old, which makes periodontitis a disease with the sixth highest prevalence [1,2]. Initiated and propagated by dental plaque...
If any of the RInChI layers are empty, they produce the string “UHFFFADPSC”. The next components are three groups of five letters, which are generated from the total protonation states and the minor InChI layers of RInChI layers two, three and four. The first letter of each group ...
Pluripotent stem cells (PSCs) form cells of all germ layers but not extraembryonic structures, such as the placenta. Embryonic stem cells (ESCs) are an example. ESCs are derived from the inner cell mass of preimplantation embryos. Another example is induced pluripotent stem cells (iPSCs) derive...
However, DPSC-induced DAergic neurons have the characteristics of immature neurons and are prone to death. The reason for the analysis may be that there is no cell niche including other cell types and extracellular matrix structure in vitro. For now, the research on the treatment of PD by ...