Biomass-derived SA is associated with low carbon footprints fueled by CO2sequestration, as commonly used biological routes for SA synthesis require CO2as a co-substrate. Recycling renewable carbon of biomass (an
Qualitative analysis of S1P production using ESI–MS In general, sphingolipid analysis via high performance liquid chromatography (HPLC) utilizes sphingoid bases-1-fluoro-2,4-dinitrobenzene (DNP) derivatives; however, S1P cannot be converted to a DNP derivative due to its negatively charged phosphate...
While the mechanism by which CLU translocates from the ER lumen to the cytosol in response to stress is yet to be elucidated, it appears that the release may form a part of a larger strategy in which many different chaperones are released from the ER to the cytosol to defend the cell ...
Computer scientists often take problems from chemistry, beat them until their bones have turned to jelly and squash them into a form suitable for a dynamic programming method. The question is, whether these approaches are really the best for problems like docking or RNA folding, where you may ...
Structure elucidation of unknown small molecules by mass spectrometry is a challenge despite advances in instrumentation. The first crucial step is to obtain correct elemental compositions. In order to automatically constrain the thousands of possible ca
DNP The Dictionary of Natural Products (DNP) from Chapman & Hall/CRC is a commercial database of natural products [23]. It arose as a daughter product of the Dictionary of Organic Compounds (DOC) that has been in book form for many years. It includes data on chemical, physical and biolo...
including: amount (dose); location (e.g. sub-organ/tissue structure, cell type, subcellular); and chemical state, in particular whether the material remains in its original nano-particulate form or is in an alternative form(s) as a result of dissolution and subsequent chemical reactions in ...
Vaccinology is one of the most important cornerstones in modern medicine, providing better quality of life. The human immune system is composed of innate and adaptive immune processes that interplay when infection occurs. Innate immunity relies on pathog
Although the origin of the eukaryotic cell has long been recognized as the single most profound change in cellular organization during the evolution of life on earth, this transition remains poorly understood. Models have always assumed that the nucleus
Nanoparticles (NPs) have been increasingly studied for radiosensitization. The principle of NPs radio-enhancement is to use high-atomic number NPs (e.g. gold, hafnium, bismuth and gadolinium) or deliver radiosensitizing substances, such as cisplatin and