Matthieu Tachon has been promoting the traditional art form of Tai Chi in his French community for a long time. An orthopaedist by day, Matthieu started his practice in the late fall of 2015 right after his first visit to the birth place of Tai Chi in Chenjiagou, China. World record ...
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Most importantly, the superior performance of MAGPIE in highly imbalanced validation dataset, as well as variants with low population allele frequency highlights its advantage in clinically relevant applications of interpreting VUS for individual patients, where the model is typically applied to identify l...
Colorectal neuroendocrine tumors with liver metastases (CRNELM) are associated with a poorer prognosis compared to their nonmetastatic counterparts. A comprehensive understanding of the tumor microenvironment (TME) heterogeneity between primary lesions (
The spatial domains detected by SpaDo form a multi-resolution schema hierarchically, enabling the characterization of spatial structures dynamically with different resolutions. In order to distinguish the spatial domains under different resolutions, we adopt the following naming scheme for the spatial domain...
The HemSCs have the potential to proliferate and disintegrate into various different cell lineages, which is one of the pathogenies of IH. The HemECs also result in a disorder of angiogenesis and further form hemangioma [7]. IHs possess kind of unique immunohistochemical markers, such as glucose...
Much it might not even be non-coding after all, tasked with functions we're simply not yet aware of. In recent years, science has increasingly moved away from describing all introns as 'junk DNA' as more possible functions are discovered, including introns being transcribed into strand...
In non-small cell lung cancer (NSCLC), naïve B cells have been shown to inhibit tumor growth [15]. However, the B-cell subtypes involved in MIBC and their functions are still not fully characterized. Tertiary lymphoid structures (TLSs) are organized aggregates of immune cells that form ...
gold nanoparticles; bleomycin; DNA damage; radiotherapy; tumor cells; cell proliferation Graphical Abstract1. Introduction According to current statistics, more than half of cancer patients receive radiotherapy (RT), and, in some cases, RT is the only treatment option [1,2]. Therefore, RT is an...
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