Therefore, we hypothesized that the increased T levels in female placentas form the n-3 LCPUFA intervention group might be due to a downregulated expression of CYP19A1. Our gene and protein expression data however show a tendatively higher gene expression in male placentas, and tendatively ...
2-PDO producer for its higher stability than that of prokaryotes [42]-[44]. An engineeredS. cerevisiaeharboring themgsgene ofE. coli-K12 MG1655 and thedhaDgene ofCitrobacter freundiiachieved 0.45 g/L 1,2-PDO in a batch fermentation [42]. The distinguished...
Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, isolated from the traditional Chinese herb Artemisia annua, is recommended as the first-line anti-malarial drug with low toxicity. DHA has been shown to possess promising anticancer activities and induce cancer cell death through apo...
Circulated iron was combined with transferrin in the form of Fe3+, and then it entered into cells by TFR1. Iron in Fe3+ form was deoxidized to iron in Fe2+ by iron oxide reductase STEAP3. Ultimately, Fe2+ was released into a labile iron pool in the cytoplasm from the endosome ...
Both tests were repeated at day 35, 42 and other days of follow up to evaluate parasite clearance times. To distinguish recrudescence form new infection, blood was collected on filter paper at day 0 and at day of parasite reappearance. The haemoglobin level was determined at day 0 and day ...
Guanine-rich sequences are able to form complex RNA structures termed RNA G-quadruplexes in vitro. Because of their high stability, RNA G-quadruplexes are proposed to exist in vivo and are suggested to be associated with important biological relevance. However, there is a lack of direct eviden...
These expression cassettes were sequentially ligated to form a multi-gene expression cassette T7mXcP4HS–T7HsAADCS–T7HsAANATS–T7HIOMTS, and the EcoRI and HindIII digestion sites were designed at both ends of the sequence. The whole sequence was chemically synthesized and identified by Sangon ...
a unique form of programmed cell death (PCD) distinct from apoptosis, necrosis, and others, has emerged as a key area of interest. However, comprehensive reviews on how natural products influence ferroptosis in respiratory diseases are lacking. This review will explore the therapeutic potential and...
The PLs and LPLs of the inner membrane, which are the substrate and product of PLA2, respectively, are highlighted in boxes; the PLs of the outer membrane are also thought to be used by PLA2. DHAP, dihydroxyacetone phosphate; ACP, acyl carrier protein; FabH, β-ketoacyl-ACP synthase;...
Data access is often restricted to project-associated users, or else the original data sets frequently remain in the hands of the scientist who created them. Another issue is the deficiency of metadata annotation. Scientists tend to use personal metadata in the form of remarks or smart file ...