Among these DEPs, serum pigment epithelium-derived factor (PEDF) was identified as a candidate biomarker using the Boruta algorithm and lasso regression. Results of ELISA further confirmed that the level of serum PEDF expression was significantly higher in axPsA (n = 37) than in pPsA (n...
map of the protein family under study. Additionally, the functional form of the energy function of the model enables us to deploy a multi-family learning strategy, allowing us to effectively integrate information across multiple protein families, whereas standard DCA algorithms are typically limited to...
Automated information extraction model enhancing traditional Chinese Medicine RCT evidence extraction (Evi-BERT): Algorithm Development and Validation. Front Artif Intell. 2024;7:1454945. Article PubMed PubMed Central Google Scholar Lin G, Huang Y, Hong-tu MI, et al. Meta-analysis of the ...
Each region displayed a distinctive protein expression pattern and eight protein clusters were established using a soft clustering algorithm [50] (Fig. 3B, Figure S1, and Table S5). Among the eight clusters, cluster 4 (C4) and cluster 6 (C6) had obvious upward and downward protein expression...
Hunicke [36] introduced the MDA (Mechanism-Dynamic-Aesthetics) framework, which outlines three fundamental design components of games. These components include (1) Mechanism: this encompasses the fundamental elements of the game at the level of data representation and algorithm, embodying the game’s...
respectively. The capillary temperature was 325 °C. The Orbitrap analyzer scanned over a mass/charge range of 81–1000 for full scans at a mass resolution of 70,000. Data-dependent acquisition (DDA) MS/MS experiments were performed with HCD scan. The normalized collision energy was 30 eV. ...
This was achieved through an advanced data-dependent acquisition (DDA) strategy, incorporating dynamic exclusion techniques to enhance and maximize the depth of coverage. The resulting data were thereafter subjected to identification through Protein Discoverer (V2.3), employing the Percolator algorithm. ...
]: This is inspired by the Google PageRank algorithm. Suppose a random walker at node i takes a random step towards any of the neighbours of i with probability α. Therefore the probability of returning to node i again is (1−α
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(variables). Subsequent preprocessing of the peak intensity data was conducted via the metaX software. Features detected in less than 50% of the QC samples or 80% of the biological samples were excluded the remaining peaks with missing values were imputed with the k-nearest neighbor algorithm to...