The finished dosage form (FDF) dossier was filed four months after the announcement of the sub-license agreement and WHO PQ was secured after nine months (or one year from the approval of the innovator product). Before the pandemic, it had taken at best three to four years to achieve WHO...
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The Wnt/β-catenin signaling pathway, also referred to as the canonical Wnt signaling pathway, is a conserved and pivotal axis in orchestrating multiple cell-signaling cascades. It plays an indispensable role in a wide range of physiological processes encompassing proliferation, differentiation, apoptosis...
Based on the instruction of the Beery-VMI, for each form, participants were asked to see the form at the top and draw the same form in the space below. After the assessment, a certified occupational therapist (RY Chen) scored the Beery-VMI based on the manual. The CAM-VMI was scored ...
The epithelial to mesenchymal transition (EMT) is implicated in many processes, ranging from tissue and organogenesis to cancer and metastatic spread. Understanding the key regulatory mechanisms and mediators within this process offers the opportunity to
A unique sequence in the KIR locus is located in the 14 kb intergenic region that separates KIR3DP1 from KIR2DL4 and divides the locus into centromeric and telomeric segments of similar size[7, 9]. This unique sequence has been the site for events of reciprocal recombination to form new ...
This standard was successfully introduced to the UK coalfields and its application was associated with a much reduced prevalence of CWP. The USA took the same data and developed their own standard of 2 mg/m3 respirable dust (measured differently from the UK) which also produced enormous ...
Ma et al. studied the relationship between five aromatic compounds (hexaldehyde, 1-octen-3-ol, γ-decalactone, 2-AP, 2,3-butanedione) and amylose in cooked rice. Experimental results showed that except for 2,3-butanedione, the other four aroma components can interact with amylose to form V...
Chronic pain conditions of the musculoskeletal system are common and of high socioeconomic relevance [1–4]. This is especially true for pain conditions with widely unknown pathogeneses, such as non-specific chronic back pain (CBP), chronic widespread pain (CWP), and fibromyalgia syndrome (FMS)...
A unique sequence in the KIR locus is located in the 14 kb intergenic region that separates KIR3DP1 from KIR2DL4 and divides the locus into centromeric and telomeric segments of similar size[7, 9]. This unique sequence has been the site for events of reciprocal recombination to form new ...